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The antibiotic streptomycin prevents protein synthesis in prokaryotes Which cell component is the most likely target of this antibiotic?
Wiki User
∙ 13y ago
Aminoglycosides such as streptomycin target protein synthesis. The antibiotic drug, streptomycin, was the first successful cure in the treatment of tuberculosis.
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∙ 9y ago
Wiki User
∙ 13y agoribosomes
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How does streptomycin kill bacterial cells?
Streptomycin is a protein synthesis inhibitor. It binds to the S12 Protein of the 30S subunit of the bacterial ribosome, interfering with the binding of formyl-methionyl-tRNA to the 30S subunit. This prevents initiation of protein synthesis and leads to death of microbial cells. Humans have structurally different ribosomes from bacteria, thereby allowing the selectivity of this antibiotic for bacteria. However at low concentrations Streptomycin only inhibits growth of the bacteria by inducing prokaryotic ribosomes to misread mRNA. It is an antibiotic that inhibits both Gram-positive and Gram-negative bacteria and is a therefore a useful broad spectrum antibiotic
Inhibitor of protein synthesis?
In prokaryotes tetracycline, chloremphenicol can inhibit protein synthesis. Puromycin is an antibiotic that inhibit both prokaryotic and eukaryotic protein synthesis. Each antibiotics has specific mode of action where it inhibits by binding, for example Chloremphenicol block the peptidyl transfer step.
How is protein synthesis different in prokaryotes and eurkaryotes?
One way that protein synthesis differs between prokaryotes and eukaryotes is that gene groups that produce proteins are organized into operons in prokaryotes, but they are not organized into operons in eukaryotes. Also, protein synthesis in eukaryotes involves more protein and is a more intricate process than in prokaryotes.
Protein synthesis in eukaryotes is similar to the process in prokaryotes in that both eukaryotes and prokaryotes?
use codons to determine polypeptide sequences
Can prokaryotes synthesize proteins?
Yes prokaryotes can synthesize proteins. Bacteria is an example of prokaryote that has 70 S ribosomes for protein synthesis. Prokaryotes do make structural and functional proteins,
How do the antibiotic actions of penicillin and streptomycin differ?
Penicillin is a beta-lactam antibiotic while streptomycin is an aminoglycoside antibiotic. Beta-lactams generally act by inhibiting transpeptidation of peptidoglycan synthesis in cell wall synthesis. Aminoglycosides interact with the 30s ribosomal subunit and inhibits protein synthesis in the cell.
How does streptomycin kill bacterial cells?
Streptomycin is a protein synthesis inhibitor. It binds to the S12 Protein of the 30S subunit of the bacterial ribosome, interfering with the binding of formyl-methionyl-tRNA to the 30S subunit. This prevents initiation of protein synthesis and leads to death of microbial cells. Humans have structurally different ribosomes from bacteria, thereby allowing the selectivity of this antibiotic for bacteria. However at low concentrations Streptomycin only inhibits growth of the bacteria by inducing prokaryotic ribosomes to misread mRNA. It is an antibiotic that inhibits both Gram-positive and Gram-negative bacteria and is a therefore a useful broad spectrum antibiotic
Inhibitor of protein synthesis?
In prokaryotes tetracycline, chloremphenicol can inhibit protein synthesis. Puromycin is an antibiotic that inhibit both prokaryotic and eukaryotic protein synthesis. Each antibiotics has specific mode of action where it inhibits by binding, for example Chloremphenicol block the peptidyl transfer step.
Prokaryotes have what structure necessary for protein synthesis?
Prokaryotes have ribosomes that are necessary for protein synthesis. The ribosomes found in eukaryotes are larger compared to those found in prokaryotes.
What is the difference between penicilin and streptomycin?
Peniciilin is derived from Penicillium chrysogenum and is active against Gram-positive bacteria. It connects peptidoglycan strands by irreversibly interacting with transpeptidase and prohibits the last cell wall synthesis. Streptomycin-sulfate is derived from Streptomyces griseusan and is an aminoglycoside antibiotic. It is active against Gram-negative bacteria and Mycobacteria and inhibits initiation of the protein biosynthesis. Penicillin and Streptomycin are often used together.
How is protein synthesis different in prokaryotes and eurkaryotes?
One way that protein synthesis differs between prokaryotes and eukaryotes is that gene groups that produce proteins are organized into operons in prokaryotes, but they are not organized into operons in eukaryotes. Also, protein synthesis in eukaryotes involves more protein and is a more intricate process than in prokaryotes.
Where does protein synthesis in prokaryotes take place?
In the cytoplasm.
Protein synthesis in eukaryotes is similar to the process in prokaryotes in that both eukaryotes and prokaryotes?
use codons to determine polypeptide sequences
Can prokaryotes synthesize proteins?
Yes prokaryotes can synthesize proteins. Bacteria is an example of prokaryote that has 70 S ribosomes for protein synthesis. Prokaryotes do make structural and functional proteins,
Why is protein synthesis different in prokaryotes and eukaryotes?
In prokaryotes, DNA is stored in the cytoplasm. also prokaryotes have no nucleus In prokaryotes, transcription and translation happen at the same time.
How is protein synthesis different in prokaryotes and eukaryote?
In prokaryotes, transcription and translation happen at the same time. -APEX Learning®️ 2021
Where does RNA and protein synthesis take place in prokaryotes and eukaryotes?
In prokaryotes, RNA synthesis and protein synthesis takes place in the cytoplasm. In eukaryotes, RNA is produced in the cells nucleus and then moves to the cytoplasm to play a role in the production of protein.
