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Buick makes a clunking sound from trans area when accelerating.
Sounds like its from one side? Ur shocks
It's either something loose or something worn out. I'd start with the shocks then look at the ball joints.
chiken
tie rod
Check the strut mountings Check springs and shocks they may be worn out
Assuming this vehicle is front wheel drive, you probably have a bad passenger side half shaft.
Wheel bearings or u joints
It is under the front side exhaust pipe. if you look up from the bottom of the car front side exhaust where it makes the 90 degree going towrds the back of the car from the passenger side you will see it
could be your crank shaft
replace c/v joints
Your brakes are probably getting low and they are rubbing against the rotor.