studies have shown that too much homocysteine in the blood is related to a higher risk of coronary Heart disease, stroke, and peripheral vascular disease
laboratory testing for plasma homocysteine levels can improve the assessment of risk, particularly in patients with a personal or family history of cardiovascular disease
High levels of homocysteine in the blood are believed to increase the chance of heart disease, stroke, Alzheimer's disease, and osteoporosis.
Treatment with folic acid and vitamins B6 and B12 lowers homocysteine levels (reducing the risk for cardiovascular problems), but more studies are needed
Treatment with folic acid and vitamins B6 and B12 lowers homocysteine levels (reducing the risk for cardiovascular problems), but more studies are needed
Treatment with folic acid and vitamins B6 and B12 lowers homocysteine levels (reducing the risk for cardiovascular problems), but more studies are needed
Frequently the cause is heart disease.
Elevated homocysteine levels are a prognostic indicator of arteriosclerosis and poor cardiovascular health. Diets rich in B vitamins, such as folic acid, B6 and B12, tend to reduce serum homocysteine levels, It is not clear whether lowering homocysteine levels in the cardiac patient will lead to improved outcomes, with respect to morbidity and mortality (especially as cardiovascular diseases tend to be multifactorial, often including a significant genetic component).
High homocysteine levels are associated with an increased risk of cardiovascular and cerebrovascular disease. Hyperhomocysteinemia can be caused by several mechanisms: (1) genetic defects in the enzymes involved in the metabolism of homocysteine, (2) nutritional deficiencies in vitamin cofactors, or (3) some chronic medical conditions and drugs. Smoking may increase homocysteine levels in the blood.In the absence of known cardiovascular or cerebrovascular disease, it is controversial whether or not to treat patients with elevated homocysteine levels. There is no clear evidence for treating patients who do not have severe hyperhomocysteinemia in the absence of cardiovascular or thrombotic disease.[1] There are conflicting data on the efficacy of supplementation aimed at lowering homocysteine levels to prevent vascular events and death in patients with established vascular disease.[2-4] For patients who are treated, the treatment should target the underlying cause, if known.In general, a diet rich in fruits, vegetables, and low-fat dairy products as well as low in saturated and total fat can help to decrease serum homocysteine. For patients with known cardiovascular disease, it is generally recommended to treat with folic acid (1 mg/day), vitamin B6 (10 mg/day), and vitamin B12 (0.4 mg/day). Folic acid can be increased up to 5 mg/day to reach a goal of lowering homocysteine levels below 15 mmol/L. In patients refractory to 5 mg/day of folic acid, 750 mg twice daily of trimethylglycine have been used, but there are only limited data demonstrating efficacy.[1] It is known that trimethylglycine enhances the methylation metabolism of homocysteine.Although treating hyperhomocysteinemia can be very important, it should go without question that the more significant cardiovascular risk factors, such as diabetes, hypertension, hypercholesterolemia, and tobacco use, must also be addressed.
It is believed that cardiovascular disease is strongly influenced by lifestyle behaviors. Since many of these behaviors are modifiable (changeable), it is logical to assume that if we change our behaviors, we can change our cardiovascular health for the better.Risk factors for developing cardiovascular disease include:SmokingConsuming a high fat/high sodium dietLack of exerciseExcessive use of alcohol and drugsExcessive stress
Homocysteine is an amino acid your body uses to make protein and to build and maintain tissue. But high levels of homocysteine may increase your risk of coronary artery disease.
The fats associated with cardiovascular disease are cholesterol and triglycerides.
There are numerous types of cardiovascular disease. The question needs to be more specific.