The description you gave was pretty vague, but this is what the 4runners with 4 doors and the 4 inch stereo opening use. I hope this helps you out.
Front speakers Dash : 4" Front Door : 5-1/4" factory speaker note
Rear speakers Rear Door : 5" factory speaker note
Far rear speakers Back Panel : 6-1/2" factory speaker note Pillar : TweeterTry to use Toyota speaker adapter plugs so you don't need to cut wires and mess the electric system up. You can get them from Ebay or Amazon.