Erwin Chargaff
Erwin Chargaff
A t g t g g a a c c g t g
The nonsense strand of the given DNA sequence T-A-C-C-A-A-G-C-T-A-C-C-T-A-T-T-A-A-C-C-G is T-A-G-G-T-T-C-G-A-T-G-G-A-T-A-A-T-G-G-C. This sequence represents the complementary base pairs to the original sequence, following the A-T and G-C base pairing rule.
Chargoff's rule was that Adenine(A) equals Thymine(T) and Cytosine(C) equals Guanine(G). Chargoff's rule was that Adenine(A) equals Thymine(T) and Cytosine(C) equals Guanine(G). (You can switch the bases around and they will still be the same!!!)
The complementary DNA strand for the given sequence is A-T-G G-C-C T-A-C G-G-T C-T-A G-T-T T-A-G. Remember that A pairs with T and C pairs with G in DNA strands.
In DNA strands, C pairs with G and A pairs with T. The complementary strand to C-C-A-T-C-G would be G-G-T-A-C.
Before we look at the complimentary mRNA sequence of the given DNA sequence, let us remember that RNA contains uracil (U) in place of Thiamine (T) The querry sequence is: t-a-c-c-t-c-g-c-a-a-c-t So the mRNA sequence would be: A U G G A G C G U U G A
It's GTTCATCCGA
G-A-T-T-A-G-C-C-T-A-A-G-G-T-C-GDNA base-pairing rulesAdenine - ThymineCytosine - GuanineRNA base-pairing rulesAdenine - UracilCytosine - Guanine
The principle that the amount of adenine (A) equals the amount of thymine (T) and the amount of guanine (G) equals the amount of cytosine (C) is known as Chargaff's rules. This observation, made by biochemist Erwin Chargaff, is fundamental to understanding the base pairing in DNA, where A pairs with T and G pairs with C, contributing to the double-helix structure of DNA.
The complementary DNA strand to the given sequence would be t c c g a g t c a g a t c g. This follows the base pairing rules where adenine pairs with thymine and guanine pairs with cytosine.
The complementary DNA strand to "ttgccagc" is "aaggctcg". In complementary base pairing, thymine (T) pairs with adenine (A) and guanine (G) pairs with cytosine (C).