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Protein hormones that need second messenger to activate a target cell are hydrophobic. They therefore need these second messengers in order to penetrate into the cell membrane.

steroid hormones are hydrophilic so they do not need second messengers.

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What is the link between a first messenger and a second messenger in a cell that responds to peptide hormones?

Peptide hormones bind to cell surface receptors, activating signaling pathways that involve the generation of second messengers within the cell. The first messenger (peptide hormone) triggers the activation of specific proteins or enzymes that then generate the second messenger molecules, such as cyclic adenosine monophosphate (cAMP) or inositol trisphosphate (IP3), initiating a cascade of cellular responses.


Which substance is called the second chemical messenger?

Cyclic AMP (cAMP) is often referred to as the second messenger in signal transduction pathways. It is a key component in mediating intracellular responses to extracellular signals such as hormones and neurotransmitters.


What is the mechanism by which protein kinase A is activated by the second messenger?

Protein kinase A is activated by the second messenger through a process called phosphorylation. When the second messenger binds to the regulatory subunit of protein kinase A, it causes a conformational change that releases the catalytic subunit. This released catalytic subunit is then able to phosphorylate target proteins, leading to various cellular responses.


Why is a second messenger not necessary in a steroid hormone?

Steroid hormones act in the transcriptional level in the nucleus of a cell, due to their ability to travel through cell membranes (hydrophillic). Second messengers are necessary for hormones that cannot penetrate cell membranes (peptides).


When a receptor protein in a cell membrane acts as a enzyme the receptor protein does what?

When a receptor protein acts as an enzyme, the receptor protein activates a second messenger that acts as a signal molecule within the cell. Resources: HOLT Biology Textbook - 9th grade edition Chapter 4, Cells and Their Environment.

Related Questions

Which type of hormone requires a second messenger?

Peptide or protein hormones require a second messenger to transmit their signal inside the cell. Upon binding to their receptor on the cell surface, these hormones activate intracellular signaling pathways that use second messengers like cAMP or Ca2+ to propagate the signal and elicit a cellular response.


What is the difference between protein hormones and steroid hormones and how they communicate with their target cells?

Steroid hormones arelipid-soluble and can dissolve easily into the cell membrane of the target cell to connect with receptors. Protein hormones are water-soluble and connect with receptors at the membrane because it can't diffuse through the membrane.


How protein and amino acid hormones react with a target cell?

The main difference between the two is that one is hydrophilic and the other is hydrophobic. This means that amino acid (peptide) hormoes cannot travel across the cellular membrane to activate genes; they must bind to receptors on the surface and activate second messenger systems. Steroid hormones, on the other hand, can travel right across membranes and affect genes directly.


Which class of hormones uses second-messenger systems?

if im not mistaken, the classes of hormones that use secondary messenger system are water soluble, nonsteroidial hormones. With this being said, all hormones that use the secondary system are protein and peptide based hormones. The cell membrane is composed phosholipid bilayer with cholestoral embedded in the membrane to allow for flexible movement.


What is the link between a first messenger and a second messenger in a cell that responds to peptide hormones?

Peptide hormones bind to cell surface receptors, activating signaling pathways that involve the generation of second messengers within the cell. The first messenger (peptide hormone) triggers the activation of specific proteins or enzymes that then generate the second messenger molecules, such as cyclic adenosine monophosphate (cAMP) or inositol trisphosphate (IP3), initiating a cascade of cellular responses.


What ion is sometimes used as a second messenger of amino acid based hormones?

Calcium ion (Ca2+) is commonly used as a second messenger of amino acid-based hormones in signal transduction pathways. It can regulate various cellular processes by binding to and activating downstream effectors such as protein kinases and phosphatases.


Cellular responses to hormones that initiate second-messenger systems include?

Possible activation of several different second messenger systems.


How do peptide hormones exert action?

The peptide hormone is used to include hormones that are peptides,proteins,glycoprotein,and modified amino acids. peptide hormones binds to a receptor protein in the target cell's plasma membrane; a realy system leads to conversion of ATP to cAMP(cyclic adenosine mono phosphate).peptide hormones are the first messenger and cAMP and calcium are the second messengers. peptide hormones does not enter the cell; second messenger sets an enzyme cascade in motion.


True or false steroid hormones perform accoding to the second messenger mechanism?

steroid hormones are hydrophobic and bind to transport proteins which bind to receptors within the nucleus. hydrophillic hormones bind to plasma membrane receptors and act through second messenger systems


Which substance is called the second chemical messenger?

Cyclic AMP (cAMP) is often referred to as the second messenger in signal transduction pathways. It is a key component in mediating intracellular responses to extracellular signals such as hormones and neurotransmitters.


What is the mechanism by which protein kinase A is activated by the second messenger?

Protein kinase A is activated by the second messenger through a process called phosphorylation. When the second messenger binds to the regulatory subunit of protein kinase A, it causes a conformational change that releases the catalytic subunit. This released catalytic subunit is then able to phosphorylate target proteins, leading to various cellular responses.


What hormone category requires g protein to activate enzymes inside a cell?

Hormones that belong to the category of peptide hormones, such as insulin and glucagon, typically require G proteins to activate enzymes inside a cell. When these hormones bind to their specific receptors on the cell membrane, they activate G proteins, which then trigger a cascade of intracellular signaling pathways. This process often involves the activation of second messengers like cyclic AMP (cAMP) or inositol trisphosphate (IP3), leading to various physiological responses.