Use acetic anhydride as reagent. The reaction will undergo nucleophilic addition and the reagent will attach to the amine group. Half of the reagent will become the leaving group and one H of the amine group in the reactant will leave with the reagent. The product will be the benzene ring with an amine, carbonyl, methyl attached.
Aniline has a higher boiling point than phenol because aniline can form strong hydrogen bonds due to the presence of an amino group. Phenol has a higher boiling point than toluene because phenol molecules can form intermolecular hydrogen bonds because of the hydroxyl group. Toluene has a higher boiling point than benzene due to the presence of a bulky methyl group which increases Van der Waals forces between toluene molecules.
Phenol is converted to aniline via the Zinin reduction reaction, which involves the reaction of phenol with ammonia and sodium metal. The phenol first forms a sodium phenoxide intermediate, which reacts with ammonia to give an amine salt. Finally, the amine salt is then reduced by sodium metal to produce aniline.
The formula is for benzyl acetate (as an example).
aniline and phenol can form hydrogen bonds with water molecules through their -NH2 and -OH groups, while nitrobenzene has no available hydrogens, but in principle can form hydrogen bonds with its oxygens with water hydrogen.As a matter of fact, the first option is more favorable than the second (e.g. butanol CH3CH2CH2CH2-OH is slightly more soluble than butanal CH3CH3CH2HC=0 in water, and the difference in solubility increases at increasing alkyl chain length).On a qualitative basis, one can think that aniline and phenol are more similar to water than nitrobenzene, hence they are more miscible.
To convert phenol to benzophenone, you can first react phenol with benzoyl chloride in the presence of a base, such as pyridine, to form an ester. Then, oxidize the ester using a strong oxidizing agent, like chromic acid or potassium permanganate, to obtain benzophenone.
React aniline with HCl/NaNO2 (diazotisation) followed by reaction with KOH to give phenol. Nitration of phenol with fuming nitric acid gives picric acid (or trinitrophenol).
In o-aniline phenol Intramolecular hydrogen bonding occurs which is not possible in meta and is responsible for less solubility
Aniline has a higher boiling point than phenol because aniline can form strong hydrogen bonds due to the presence of an amino group. Phenol has a higher boiling point than toluene because phenol molecules can form intermolecular hydrogen bonds because of the hydroxyl group. Toluene has a higher boiling point than benzene due to the presence of a bulky methyl group which increases Van der Waals forces between toluene molecules.
Phenol is converted to aniline via the Zinin reduction reaction, which involves the reaction of phenol with ammonia and sodium metal. The phenol first forms a sodium phenoxide intermediate, which reacts with ammonia to give an amine salt. Finally, the amine salt is then reduced by sodium metal to produce aniline.
This reaction is also called p-Hydroxy methylation of Phenol and phenol is converted into p-hydroxy benzyl alc.
The formula is for benzyl acetate (as an example).
Phenol is converted to aspirin by adding carboxylic acid and esterifying the alcohol.
aniline and phenol can form hydrogen bonds with water molecules through their -NH2 and -OH groups, while nitrobenzene has no available hydrogens, but in principle can form hydrogen bonds with its oxygens with water hydrogen.As a matter of fact, the first option is more favorable than the second (e.g. butanol CH3CH2CH2CH2-OH is slightly more soluble than butanal CH3CH3CH2HC=0 in water, and the difference in solubility increases at increasing alkyl chain length).On a qualitative basis, one can think that aniline and phenol are more similar to water than nitrobenzene, hence they are more miscible.
Aniline is used in the synthesis of numerous pharmaceutical compounds. It serves as a starting material for the production of various analgesics, antipyretics, and anti-inflammatory drugs. Additionally, aniline derivatives are employed in the synthesis of certain antibiotics, antimalarials, and antitumor agents.
To convert phenol to benzophenone, you can first react phenol with benzoyl chloride in the presence of a base, such as pyridine, to form an ester. Then, oxidize the ester using a strong oxidizing agent, like chromic acid or potassium permanganate, to obtain benzophenone.
Hydrochloric acid (HCl) is added to the solution during the estimation of phenol to convert phenol into its corresponding chloride salt, which is easier to separate and quantify. This reaction helps in the extraction and analysis of phenol from the sample.
Anisole can be converted into phenol by using a strong aqueous acid, such as hydrochloric acid, in the presence of water and heat. The acidic conditions will cleave the methoxy group (–OCH3) from the benzene ring, resulting in the formation of phenol. This reaction is known as hydrolysis of an ether.