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When acetylcholine diffuses across the synaptic cleft and binds to receptors on the folded sarcolemma it initaly causes what channels to open in the sarcolemma?

Acetylcholine binding causes nicotinic acetylcholine receptors on the folded sarcolemma to open, allowing the influx of sodium ions into the muscle cell. This initiates an action potential that propagates along the sarcolemma and into the T-tubules, triggering muscle contraction.


A folded region of the sarcolemma at the neuromuscular junction?

The folded region of the sarcolemma at the neuromuscular junction is called the motor end plate. It is responsible for receiving signals from the motor neuron and initiating muscle contraction. The motor end plate is rich in acetylcholine receptors, which play a key role in neurotransmission at the neuromuscular junction.


What receptor is responsible for the secretion of salivary amylase?

The muscarinic receptors on the salivary gland cells are responsible for the secretion of salivary amylase. Stimulation of these receptors by the neurotransmitter acetylcholine triggers the release of amylase into the saliva.


Does atropine block only nicotinic receptors?

Atropine does not only block nicotinic receptors but also acetylcholine at muscarinic receptors


What best describes how ACh changes the ion permeability of the sarcolemma?

Acetylcholine (ACh) binds to nicotinic receptors on the sarcolemma of muscle fibers, leading to the opening of ion channels. This results in an influx of sodium ions (Na+) into the cell, which depolarizes the sarcolemma and initiates an action potential. The change in ion permeability is crucial for muscle contraction, as it propagates the signal to the interior of the muscle fiber and ultimately stimulates the release of calcium ions from the sarcoplasmic reticulum.

Related Questions

Which neurotransmitter receptor is present on the sarcolemma?

Acetylcholine receptor is present on the sarcolemma of the muscle cells. This receptor is responsible for transmitting the signal to initiate muscle contraction when acetylcholine binds to it at the neuromuscular junction.


When acetylcholine diffuses across the synaptic cleft and binds to receptors on the folded sarcolemma it initaly causes what channels to open in the sarcolemma?

Acetylcholine binding causes nicotinic acetylcholine receptors on the folded sarcolemma to open, allowing the influx of sodium ions into the muscle cell. This initiates an action potential that propagates along the sarcolemma and into the T-tubules, triggering muscle contraction.


At the neuromuscular junction, the muscle contraction initiation event is?

 binding of acetylcholine to membrane receptors on the sarcolemma


What is the role of acetylcholine in skeletal muscle contractions?

acetylcholine as far as i know is a neurotransmitter that ativates the mscle cells.


A folded region of the sarcolemma at the neuromuscular junction?

The folded region of the sarcolemma at the neuromuscular junction is called the motor end plate. It is responsible for receiving signals from the motor neuron and initiating muscle contraction. The motor end plate is rich in acetylcholine receptors, which play a key role in neurotransmission at the neuromuscular junction.


The two types of receptors that bind acetylcholine are?

nicotinic acetylcholine receptors (nAChR, also known as "ionotropic" acetylcholine receptors) are particularly responsive to nicotinemuscarinic acetylcholine receptors (mAChR, also known as "metabotropic" acetylcholine receptors) are particularly responsive to muscarine.Nicotinic and muscarinic are two main kinds of "cholinergic" receptors.


Where are acetycholine receptors found?

In the Sarcolemma


The axon terminals of a nerve cell and the sarcolemma of a skeletal muscle cell join at the?

The axon terminals of a nerve cell and the sarcolemma of a skeletal muscle cell join at the neuromuscular junction. This is where the nerve impulse triggers the release of neurotransmitters, such as acetylcholine, which initiate muscle contraction by binding to receptors on the sarcolemma.


What receptor is responsible for the secretion of salivary amylase?

The muscarinic receptors on the salivary gland cells are responsible for the secretion of salivary amylase. Stimulation of these receptors by the neurotransmitter acetylcholine triggers the release of amylase into the saliva.


Does atropine block only nicotinic receptors?

Atropine does not only block nicotinic receptors but also acetylcholine at muscarinic receptors


Receptors for acetylcholine are located on the?

Acetylcholine receptors are located on the motor end plate or postsynaptic sarcolemma. Otto Loewi was a German pharmacologist whose discovery of acetylcholine earned the 1936 Nobel prize in Physiology or Medicine which he shared with Sir Henry Dale. Acetylcholine is a neurotransmitter. Neurotransmitters are chemicals that transmit signals from a neuron to a target cell across the synapse and most are synthesized at the nerve terminals.


What is ACh receptors?

ACH receptors can be defined as an integral membrane protein that responds to the binding of acetylcholine, a neuoyansmitter. Two example are nicotinic acetyl line receptors and muscarinic acetylcholine receptors. .