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Anemia

This category is for questions about the lack of red blood cells or hemoglobin called anemia: its symptoms, causes, and treatment.

936 Questions

What is polychromasia in humans?

Polychromasia in humans is due to red blood cells that are released from the marrow before they are fully developed. New cells appear sort of blue in staining. Old cells appear orange. The term polychrom- means many colors.

The blue cells are called reticulocytes. This is due to the fibers that are not removed yet. This is due to the fact that they are sort of rushed out to do their work.This is often a sign of anemia. Anemia is a lack of red blood cells. One has to rule out bleeding or an immune problem.

Does sickle cell disease cause stroke?

Approximately 11% of individuals with sickle cell disease will have a recognizable stroke by the age of 20

Can anemia make you more thirsty?

Perhaps it would make you thirsty. The body may be trying to make more volume in the blood.

Antiparietal cells antibodies test?

Definition

The antiparietal cells antibodies test measures the presence of antibodies against the parietal cells of the stomach. The parietal cells make and release intrinsic factor and stomach acid. Intrinsic factor is needed to absorb vitamin B12.

Alternative Names

APCA; Anti-gastric parietal cell antibodies

How the test is performed

Blood is typically drawn from a vein, usually from the inside of the elbow or the back of the hand. The site is cleaned with germ-killing medicine (antiseptic). The health care provider wraps an elastic band around the upper arm to apply pressure to the area and make the vein swell with blood.

Next, the health care provider gently inserts a needle into the vein. The blood collects into an airtight vial or tube attached to the needle. The elastic band is removed from your arm. Once the blood has been collected, the needle is removed, and the puncture site is covered to stop any bleeding.

In infants or young children, a sharp tool called a lancet may be used to puncture the skin and make it bleed. The blood collects into a small glass tube called a pipette, or onto a slide or test strip. A bandage may be placed over the area if there is any bleeding.

The blood is sent to the lab, where the liquid portion of the blood (serum) is separated from the cells. A sample of the serum is placed on a slide with samples from a mouse kidney and stomach, which contain parietal cells. If your serum contains parietal cell antibodies, these antibodies will react with the parietal cells on the slide.

How to prepare for the test

No special preparation is necessary.

Why the test is performed

Your health care provider may use this test to help diagnose pernicious anemia. Other tests are also used to help with the diagnosis.

Normal Values

The test is negative.

What abnormal results mean

A positive test result may indicate:

What the risks are

Veins and arteries vary in size from one patient to another and from one side of the body to the other. Obtaining a blood sample from some people may be more difficult than from others.

Other risks associated with having blood drawn are slight but may include:

  • Excessive bleeding
  • Fainting or feeling light-headed
  • Hematoma (blood accumulating under the skin)
  • Infection (a slight risk any time the skin is broken)
Special considerations

Less than 2% of the general population test positive for antiparietal cell antibodies. However, that percentage increases with age. Some people over age 60 may test positive for antiparietal cell antibodies.

Persons with other immune disorders such as thyroiditis and type 1 diabetes may also have antiparietal cell antibodies.

References

Antony AC. Megaloblastic anemias. In: Goldman L, Ausiello D, eds. Cecil Medicine. 23rd ed. Philadelphia, Pa: Saunders Elsevier;2007:chap 170.

Is sickle cell disease dominant or recessive?

The disease is recessive, requiring both parents to carry the allele for the disease to be found in the offspring.

If one parent has it, the offspring can also be a carrier, but it will be recessive, and the offspring will have normal RBC (red blood cells)

What causes warm antibody hemolytic anemia?

This condition occurs when the body produces autoantibodies that coat red blood cells. The coated cells are destroyed by the spleen, liver, or bone marrow.

What is the danger of a eight year old child being diagnosed with Normochromic anemia with reversed necrophilia's?

You have the wrong adjectives here! Necrophilia is a morbid turn-on to the deceased, love of the dead, literally. ( Necrology is an old word for the obituary files). Anemia is a low-blood circulation disease- Necrophilia is a mental twist! Maybe you mean hemophilia- which is a very serious health problem ( uncontrolled bleeding) It is almost always in the Male, but females can carry the disease, as in the Russian royal family. Somebody said all the girls had it except the youngest- Stacy- which may be why she survived.

Can anemia lower your ability to fight off infections?

Anemia affects red blood cells usually, and doesn't always lower the immune system response but aplastic anemia (a.k.a bone marrow failure) causes the body to produce less red blood cells, WHITE blood cells, and platelets. Therefore, I believe, anemia can lower your ability to fight off infections (if the amount of white blood cell production is lowered). the above answer is true but people with sickle-cell anemia have a greater resistance to malaria. Also aplastic anemia patients have just as much troube as fighting a VIRUS as any other person.

Are there prenatal tests for sickle cell anemia?

Yes, there are prenatal tests for sickle cell anemia, which can be performed during pregnancy to determine if the fetus has the condition or carries the sickle cell trait. Common methods include chorionic villus sampling (CVS) and amniocentesis, both of which analyze fetal DNA. Additionally, non-invasive prenatal testing (NIPT) can assess the risk of sickle cell disease based on the parents' genetic profiles. These tests help parents make informed decisions regarding their pregnancy and potential management options.

What population of people does sickle-cell effect more than others?

Sickle-cell anemia affects black people more than other groups. There is some indication that sickle-cell gives a survival benefit for some tropical diseases, such as the Malaria parasite.

Does anaemia make you weak?

Yes anaemia can make you weak. This is because the body has a lower number of haemoglobin molecules, which are the molecules in red blood cells which carry oxygen around the body. Therefore, the body tissues are receiving less oxygen and can not work as effectively.

What do you do if you love someone and both of you have the thalassemia minor trait?

I knew that I have this trait but loved a girl who was incidently found to be a carrier when she got prgnant after our marriage. Any we got a haematologist's cosult and on his prescription my wife went under investigation for baby in her womb. And with 3rd baby al-hamdu-li-Allah all are normal for tests and one boy 7years and a girl 2years are active and healthy. Third one to be born in feb. 2005. Inshallah. I think this should be kept in mind that woman has to go under painful procedures and if Allah forbid baby is abnormal(ie Thalassemia Major) he or she has to be terminated before 12 week of gestational age to avoid the misserable life later on.For that you ought to be bold if you dare to marry. Happy marriage.

What does anemia and high platelet count indicate?

it could indicate blood loss, iron deficiency or an inflammatory/reactive condition

Is Cooley's Anemia found more commonly in certain groups of people?

The original term for cooley's anemia, is Mediterranean anemia. People from the Mediterranean origin tend to develop this disease more commonly. Children can inherit it from one of their parents.

Does levaquin cause anemia?

Just got back from a visit to a hematologist, after being referred by my primary care physician. The concern was a persistent mild anemia, with a count of 10.8. I also have a chronic sinus infection for which I was prescribed 24 day course of Levaquin tabs. The hematologist said that she thinks that the sinus infection along with the Levaquin, or either alone is enough to cause the anemia. She had my blood drawn to check iron levels and sedimentation rate. Hope to hear in a few days. But the take away on Levaquin is that it can cause anemia.

Can you rub a nickel on your skin to see if you have anemia?

It would appear so. If you see black lines after you rub a nickel on your skin, you just might be anemic. Of course, if you rub a really dirty nickel on your skin you might get a false reading. Best see a doctor.

What cause pernicious anemia?

Pernicious Anemia is caused by a lack of intrinsic factor (usually). There can be other causes, such as infection, surgery, medicines taken, or diet.