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Drugs and Grapefruit

Drugs when taken together with grapefruit may result to undesirable drug interactions. Grapefruit contains ‘naringin’ which affect drug absorption and inhibit the CYP3A4 enzyme in the small intestines. Patients taking cyclosporine are advised not to take grapefruit juice.

193 Questions

Can I eat grapefruit if taking Losartan Potassium?

It's generally advised to avoid grapefruit while taking Losartan Potassium. Grapefruit can interfere with certain medications by affecting how they are metabolized in the body, potentially leading to increased side effects or reduced effectiveness. It's always best to consult with your healthcare provider for personalized advice regarding your medications and dietary choices.

Can you eat grapefruit when taking Telmisartan?

It's generally advised to avoid grapefruit while taking Telmisartan, as it can interfere with the metabolism of certain medications. Grapefruit may increase the concentration of the drug in the bloodstream, potentially leading to increased side effects. Always consult your healthcare provider for personalized advice regarding dietary restrictions while on medication.

Is it safe to eat a grapefruit while taking valtrex?

Yes, it is generally safe to eat grapefruit while taking Valtrex (valacyclovir). There are no known interactions between grapefruit and Valtrex that would cause concern. However, it's always a good idea to consult with your healthcare provider or pharmacist about potential interactions with any medications you are taking.

Can you eat grapes while taking lercanidipine?

Yes, you can generally eat grapes while taking lercanidipine. There are no known significant interactions between lercanidipine and grapes. However, it's always a good idea to consult your healthcare provider or pharmacist regarding your diet and any potential interactions with medications.

What happens if you eat grapefruit while taking suboxone?

Eating grapefruit while taking Suboxone (a medication used to treat opioid addiction) can increase the levels of buprenorphine in the bloodstream. Grapefruit inhibits certain enzymes in the liver, specifically CYP3A4, which are responsible for metabolizing buprenorphine. This can lead to enhanced effects and potentially increase the risk of side effects or overdose. It’s important to consult with a healthcare provider about dietary restrictions when taking Suboxone.

Can you eat sprouts while taking waferin?

While on warfarin, it's important to manage your vitamin K intake, as it can affect the medication's effectiveness. Sprouts, particularly those like alfalfa and clover, can be high in vitamin K. It’s advisable to consult with a healthcare provider or nutritionist to determine a safe amount of sprouts you can consume while on warfarin, ensuring that your diet remains consistent.

Can you eat grapefruit while talking vitamin d3?

Yes, you can generally eat grapefruit while taking vitamin D3. However, grapefruit can interact with certain medications by affecting their metabolism in the liver, which may lead to increased levels of those drugs in the bloodstream. While vitamin D3 is not known to have major interactions with grapefruit, it's always best to consult with a healthcare professional if you're on medication or have specific health concerns.

What is in grapefruit that makes it interact with medicines?

Grapefruit contains compounds known as furanocoumarins, specifically bergamottin and dihydroxybergamottin, which inhibit the activity of an enzyme called CYP3A4 in the intestines. This enzyme is responsible for metabolizing many medications. When CYP3A4 is inhibited by grapefruit compounds, it can lead to higher levels of certain drugs in the bloodstream, potentially causing adverse effects or toxicity. It is important to be cautious of grapefruit-drug interactions and consult with a healthcare professional if you have any concerns.

What will happen if you are on citalopram and eat grapefruit?

Most probably nothing.

The same enzym in the liver is used to metabolize the grapefruit as well as the citalopram, so a slight increase of the citalopram-level could occur.

But one grapefruit every now and then shouldn't be a problem I guess.

Why you cannot mix grapefruit and simvastatin?

why can't you drink grapefruit with zocor or simvastatin:

The risk of myopathy and rhabdomyolysis is increased by high levels of statin activity in plasma. Simvastatin is metabolized by the cytochrome P450 isoform 3A4. Certain drugs which inhibit this metabolic pathway can raise the plasma levels of simvastatin and may increase the risk of myopathy. These include itraconazole, ketoconazole, and other antifungal azoles, the macrolide antibiotics erythromycin and clarithromycin, and the ketolide antibiotic telithromycin, HIV protease inhibitors, the antidepressant nefazodone, or large quantities of grapefruit juice ( > 1 quart daily).

Can you eat grapefruit while on Zoloft?

Grapefruit juice acts as a potentiator when it comes to xanax. In other words, when the two are mixed, the xanax will hit you harder and much quicker than it would as prescribed by your doctor. So if you were prescribed xanax as a remedy for anxiety or panic attacks, it would probably just knock you out instead, especially since xanax already has a big "drowsy" side effect to it.

Hope that helped answer your question.

You are on Warfarin can you eat grapefruits?

I believe I was told that it would just make the Lexapro not work, which could send your body into dangerous withdrawls, if you've been on it awhile, but call your Pharmasist or doctor and make sure.

Is grapefruit bad for you if you have high blood pressure?

No, because cozaar is an angiotensin receptor blocker which lowers the blood pressure & grape fruit will block some enzymes in the interstine so that the medication directly can enter in to the body very fast &in the kidneys there will be loss of water &salts . it causes so many side effects .

Can you eat grapefruit skin while taking cholestorol meds?

If consumed in large enough quantities (some have said over a quart daily), grapefruit juice contains some compounds which compete for the same enzyme pathways of metabolism in the liver as do cholesterol and many other meds. Many dietitians have therefore removed grapefruit juice from hospitals .

Can you eat grapefruit while taking the mini pill?

I did a quick check of the literature and could not find any warnings about grapefruit and olmetec. However, I have read generally that grapefruit tends to make it so more of a medication get absorbed into your system than can be expected through the normal digestive process and hence the effects of the medication are strengthened which may not be a good thing. Double check with your doctor. Whatever they say should be good advice.

Is it safe to eat grapefruit while taking triamterene hctz?

If you take amlodipine -- or any other kind of calcium channel blocker -- do not take them with grapefruit, grapefruit juice or grapefruit dietary supplements, because serious, possibly fatal, reactions may occur. Grapefruit inhibits your CYP34A enzyme, a protein that helps your body metabolize drugs. When your body fails to properly metabolize drugs, you may end up with more of amlodipine in your system than intended, causing an accidental overdose. Some drugs -- and some people -- react more strongly than others to the effect of grapefruit on your CYP34A enzyme.

Does grapefruit or juice effect Hyzaar medication?

Yes you can, it will cause more fluids to leave the body, the same as lemons and oranges

How many ounces of juice in a grapefruit?

On average approximately 3-4oz. Don't refrigerate citrus before squeezing and you will get more juice.

Why cant you eat grapefruit and take lipiture medications?

grapefruit juice interacts with many many drugs... but usually it is only a mild interaction perhaps slightly increasing or decreasing the potency of some medications. but your pharmacist is trained to know these things he is the one to call.

What meds does grapefruit interact with?

Dextrometorphan should not be taken with Grapefruit as you will probably get hallucinations.

Edit: If you are taking normal doses of dextrometorphan and you do not have a rare sensitivity to it (because of an enzyme in your liver, or lack thereof), then grapefruit will have no effect whatsoever. As a matter of fact the relation between eating grapefruit and the effectiveness of dextrometorphan has not been successfully demonstrated. The problem with grapefruit-drug interactions is that sulfur-compounds in grapefruit juice may affect the way many meds are metabolized in the liver. This involves many antihypertensive and cholesterol-lowering agents and should probably be avoided.