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Klinefelter's Syndrome
Klinefelter's syndrome is the condition first described in 1942 in which males have an extra X sex chromosome, also known as XXY syndrome. It is the most common sex chromosome disorder, affecting 1 in 1000 males. The effects often include small testicles, decreased fertility, increased breast size, less facial hair, and learning disabilities.
140 Questions
Does klinefelter syndrome male have Adams apple?
Yes. The Adams apple may not grow during puberty as will do with other males.
Can you have wet dreams with Klinefelter's syndrome?
Yes, but not everyone with KS can. Sometimes HRT fixed it, sometimes it doesn't.
Why does everybody with klinefelter's syndrome end out to be a male?
All people with Klinefelter's syndrome are male because by definition Klinefelter's syndrome is due to a genotype of XXY. The fetus will develop into a male if there are any Ys present at the sex chromosome.
What chromosomal abnormality causes Klinefelter syndrome?
46,XXY or XXY for males; see the link below.
What is the cause of Klippel Feil syndrome?
Klippel Feil syndrome is believed to occur during very early fetal development, when the cervical vertebrae do not segment normally. The exact mechanism that causes the defect is unkown
What are the statistics of Klinefelter's syndrome?
In the United States approximately 1 in 500 to 1 in 1000 male live births are affected with the syndrome. See the link. (my endrocronologist - who has been in practice 35+ years has never seen another klinefleters patient and we live in Boston. Many people who have it - that never desire children may never be diagnosed. therefore I think the number is closer to the one in a 1000
Why x-chromosome are also called Barr body?
That is what random X chromosomes do in the female somatic cells. They form Barr bodies. This is a methylated X chromosome that effectively shuts this chromosome down, one per cell in a random manner. This is done by the body because too much protein product is detrimental to organisms.
What specialist would you see for Klinefelters syndrome?
For Klinefelter syndrome, individuals should consult an endocrinologist, who specializes in hormone-related disorders, to address issues related to testosterone deficiency and other hormonal imbalances. Additionally, a geneticist can provide insight into the chromosomal aspects of the condition. Depending on specific needs, a urologist or fertility specialist may also be involved, especially for concerns related to reproductive health.
Can you serve in the military with klinefelter's syndrome?
Most males with Klinefelters syndrome have sufficient physical and potentially mental development issues to render them unsuitable for millitary service.
This does not preclude the fact that there are always exceptions.
What causes disorders such as Klinefelter's syndrome and Turner syndrome?
Klinefelter's syndrome is caused by the presence of an extra X chromosome in males (XXY), typically resulting in developmental and hormonal differences. Turner syndrome is caused by the complete or partial absence of one of the X chromosomes in females (X0), leading to underdeveloped ovaries and infertility. Both conditions occur due to chromosomal abnormalities during conception.
Does Klinefelter's syndrome affect a particular population or race?
No race is more likely to spontaneously have issues with meiosis, and as Klinefelter's is not hereditary (anyone with it is infertile and cannot pass on genes) no race will become more likely to have Klinefelter's syndrome.
The population of older women who have children is more likely to have Klinefelter's babies. Older women are less likely to miscarry a baby with a chromosomal defect, so more Klinefelter's babies are born to them.
