Klinefelter's Syndrome

Mutation of a gene is not necessary for Klinefelter's Syndrome. It is an autosomal disorder meaning that an entire chromosome failed to disjunction during anaphase and so there are 2 X chromosomes and a Y chromosome.

No, they cannot reproduce because they start developing hormones late in life therefore their sperm is infertile, and they have a small penis, redering them unable to have sex. which means no babies.

It will not be able to revive

it will be digested by its lysosome

No. Do to the fact that when parents pass on the genes the father only ever gives the Y. What happens in XXY is that for some reason the mother gives both X's or potentially their is a defect with the replication of the cell during development. So while their is a small chance it is not very likely. Also you have to realize the a male with XXY is most likely going to be sterile, however this is not always the case.

The karyotype of the asexual organism would not contain homologous chromosomes

A trisomy. A monosomy is when there is only one of a chromosome. A trisomy is when there are three of a chromosome. In Klinefelter's syndrome, there are three sex chromosomes.

I don't know tell me the answer

I am afraid is quite an in-depth subject.

in layman's terms, if you imagine a glass slide with lots of very small dots (500,000 of them). these dots (probes) are complementary DNA, which has been stuck to the slide.

If you then take a sample of mRNA (expressed DNA) from the patient and turn it into DNA (cDNA). If you then put that cDNA on top of the dots on the slide and incubate, if that patients gene is being expressed it will bind to the probes stuck on the glass. This binding to the probe causes fluorescence, which can be detected.

If you compare the expression patterns between a healthly individual and a diseased individual you can try and work out what genes are being expressed differently in that condition (for research purposes). If you already know a certain gene is over expressed in a disease (e.g. BRAC2 in breast cancer), you can then diagnose the patient.

Likewise you can use microarrays to predict what diseases you may develop in the future - for example you may be found to have a gene found in Alzheimer's for instance.

This is a very very brief introduction to the subject and its very interesting, you may like to try the following link if you'd like some more information on the subject.

http://plasticdog.cheme.columbia.edu/undergraduate_research/projects/sahil_mehta_project/work.htm

This condition is not inherited; it usually occurs as a random event during the formation of reproductive cells (eggs and sperm). An error in cell division called nondisjunction results in a reproductive cell with an abnormal number of chromosomes. For example, an egg or sperm cell may gain one or more extra copies of the X chromosome as a result of nondisjunction. If one of these atypical reproductive cells contributes to the genetic makeup of a child, the child will have one or more extra X chromosomes in each of the body's cells.

Mosaic 46,XY/47,XXY is also not inherited. It occurs as a random event during cell division early in fetal development. As a result, some of the body's cells have one X chromosome and one Y chromosome (46,XY), and other cells have an extra copy of the X chromosome (47,XXY).

they have a extra chromosome, a normal male is XY, a male with klinefelters is XXY.

Testosterone injections started around the time of puberty may help to produce more normal development including more muscle mass, hair growth and increased sex drive. Testosterone supplementation will not increase testicular size.

Klinefelter's is not a hereditary disease in that it is not passed from one generation to the next. Klinefelter's occurs when the mother's egg does not separate correctly, so instead of there being one X in the egg's chromosome, there are two. So when it joins with the father's sperm, it forms an XXY. But the man with Klinefelter's is almost invariably infertile.

According to the National Institute of Neurological Disorders and Stroke (NINDS), megalencephaly is one of the cephalic disorders, congenital conditions due to damage to or abnormal development of the nervous syst

No, as people with Klinefelter's syndrome cannot have children and so there would not be another generation. (That is not entirely true, while it is true Klinefelters causes an extra chromosome sperm maybe be found via a testicular extraction in minute amounts. If this is the case you can father a biological child though the chances are small it is not impossible and more and more Klinefelter men are becoming dads. We can also adopt, and while I understand the authors point - the child would be ours and therefore carry our name and continue the generation. Klinefelters IS NOT hereditary. Hope this helped.

A karyotype is basically a chart of the number and structure of chromosomes. They can reveal ploidy differences (missing or additional chromosomes such as trisomy 21) or chromosomal mutations (like inversions, deletions, translocations etc)

People with Klinefert´s syndrome have one barr body.

Yes , the number of barr bodies in a cell is always equal to the number of X chromosomes minus one. For example in the XXY chromosome there is one Barr body

Not really.

Klinefelter's Syndrome is a genetic issue and as such is NOT preventable at our current level of technology.

I guess it may be possible to check the gene of a foetus and abort if the genotype indicates the condition but that is way too harsh a solution as Klinefelters does not necessarily mean a significantly reduced quality of life for sufferers.

What is relatively easy to address is the symptoms of Klinefelters and the 'golden standard' for treatment is the application of testosterone.

A site that tells you all about Klinefelters is:

http://www.klinefeltersyndrome.us/symtomsinboy.html (symptoms in boys)

they also have a page on the symptoms in men and another on treatment of symptoms.

A karyotype is the number and appearance of chromosomes in the nucleus of a eukaryote cell. There are 46 chromosomes in a human karyotype. However, there are twenty-three pairs. In a karyotype, chromosomes are showed in pairs, because twenty-three are from one parent, and twenty-three are from another. In a cell, there are twenty-two pairs of chromosomes called autosomes, and one pair of sex chromosomes. The sex chromosomes are different in a male and a female. For a male, it is one x chromosome and one y chromosome. In a female, it is two x chromosomes. So, as a recap, there are 46 chromosomes. The only exceptions to this are autistic people. For them, there is usually a duplication or deletion of one chromosome. In other words, a person would have 47 or 45 chromosomes.

Yes, but when it happens you get retards (mentally disabled people)

Yes, klinefelters is waiverable in the us army but the marines or navy will disqualify you if they find out.

it would make for a defective baby!

no, its not immediately but life can be shortened due to deficiencies. A male not on HRT can not bind calcium to bones and muscles. Over time deficency can result in premature failure of heart, osteoporosis, decrease in immunity, sleep quality. Thus resulting in death.

People with Klinefelter's syndrome are not hermaphrodites, and people who are hermaphrodites do not have Klinefelter's syndrome.