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Sickle-Cell Disease

Sickle-cell disease is a genetic blood disorder wherein the red blood cells are irregularly shaped due to the blood’s lowered oxygen tension. This irregularity may result in chronic anemia, serious infections, painful conditions, damage to organs and death.

538 Questions

How Sickle Cell Disease Can Affect The Body?

Sickle Cell Disease is a blood disorder that is permanent. It is a lifelong struggle for those who have it. Those suffering from the disease need to take a variety of medications in order to maintain their health and survive.

Is sickle cell anemia a disease from mutation?

Yes, but the mutation happened many many thousands of years ago. It has been passed on through all these generations because the same gene that causes sickle cell anemia in a person that inherits two copies of the gene also causes resistance to the malaria parasite in a person that inherits only one copy of the gene.

In areas of the world where malaria is a common disease, the resistance to it is a stronger selective advantage than sickle cell anemia is a selective disadvantage; so the gene becomes very common in those populations.

Can mixed race get sickle cell disease?

lol that's a dumb question

and that's a dumb answer. Yes it is always possible, to some tiny degree. The risk factor is dependent on the specific races involved. For example a person of African decent has a higher risk, than a person of hispanic or Mediterranean, and caucasian is the lowest risk of all. If one parent is caucasian the risk is pretty small. among 2 caucasians, not of middle eastern or Mediterranean, non jewish, the risk is smallest.

What type of disorder is sickle cell disease?

It is when your body does not produce alot of blood and you become very skinny and sick. It can be passed on to babies by mothers and mostly occurs in African countries and some parts of Asia, too.

Do primates have sickle cell anemia?

That is very interesting question, indeed. Your concern for the primates needs appreciation. The answer to this question is probably positive. Sickle cell anaemia is a natural selection in malaria endemic zone. The sickle cell trait patient is genetically resistant to malarial fever. So many primates suffer from malarial fever. From this finding you can say that sickle cell anaemia should be present in primates, who live in tropical countries.

What is sickle cell anemia hemophilia and leukemia?

They are both genetic blood disorders, which are inherited from the parents.

Sickle cell anemia is caused by a mutation in the gene responsible for hemoglobin. If a person has inherited the mutation, their bone marrow will produce sticky, sickle-shaped red blood cells, which cause a wide array of issues.

Hemophilia is another blood disorder that is inherited from the parents, but in a different and more complicated way. Hemophiliacs (people suffering from hemophilia) have a problem with blood clotting. They will always bruise easily, and when they bleed, the blood might not clot unless certain actions are taken.

Both diseases affect the blood, and are life long. There are currently no effective cures for them.

How do you treat patients that suffer from anemia be treated?

My brother had iron-deficiency anemia as a kid and he had to take pills to help raise his iron-levels. There are also iron-filled foods that can raise the level naturally, including beans and spinach. (It wasn't Popeye's source of strength for no reason.)

Why does the spleen enlarge in sickle cell?

Because the spleen is responsible for destruction of abnormal red blood cells; therefore since sickle cell causes abnormalities in red blood cells, the spleen works extra hard for extended periods of time to remove them.

What is the advantage of being heterozygous for the sickle cell allele?

Sickle cell trait carries a lower risk of serious malarial disease, without the signs and symptoms of sickle-cell anemia.

Does sickle cell only affect black people?

Sickle cell appears in several geographical regions in the world and is attached to different genes in those areas. It appears where malaria is endemic. The African form is the most common. Different forms developed in Southern Greece, Southern Afghanistan, and a few other places. The African form affects Black people.

What are the odds of getting sickle-cell anemia?

Sickele-Cell Anemia ia one one of the most common genetic blood disorders.

Why are are people with the sickle cell trait able to resist malaria?

Sickle cell anemia is a genetic diseases that causes red blood cells to be shaped like sickles while normal red blood cells are shaped more like a cylinder. Malaria works by going into the red blood cells until they burst. Because of the strange shape of the red blood cells in people who have sickle cell anemia, malaria can't enter in the cells that have the sickle trait, but it can enter in the others. This way, people with sickle cell wouldn't be as adversely effected then those without it.

What does a sickle cell blood so look like?

people with sickle cell disease have no abnormal appearances. the abnormalities are found on the microscopic level when the blood cells are examined.

Dangers of alcohol?

it is dangerous because it messes up your depth perception.

And it makes you feel invisible

Alcohol alters your brain so your not always in control.

Alcohol alters your ability to drive.

Alcohol causes liver damage and loss of brain cells.

What groups get sickle cell disease?

A person can only inherit sickle-cell genes if some of their ancestors came from certain regions in Africa where the inhabitants carry sickle-cell genes.

A person with one sickle-cell gene has sickle-cell trait, a milder problem.

If both father and mother pass on sickle-cell genes, the child, with two genes, will have sickle-cell disease.

How does sickle cell impacts on community and society?

health social and economic implications of sickle cell diseases.

What does poikilocytosis mean?

Having poikilocytes in your blood - which are irregular red blood cells

What is the sickle cell trait of sickle cell anemia?

The sickle cell trait is that you dont have the whole thing you have half of it which is called the trait

How is Sickle Cell Anemia influenced by environmental factors?

In the cold seasons the patient will suffer from joint pains, and in the high places like mountain they will suffer also from severe pain.

Where did sickle cell come from?

sickle cell orignates when a red blood cell is too large to fit in the blood vessel and the pressure that is against the it causes it to have a crescent shape