Sickle-Cell Disease

The stomach and heart/lungs.... This person who previously answered this question with just those 3 things also forgot some major organs... Pancreas, Liver, Upper Intestines, Lower Intestines (the L.I. are right behind the belly button)

It affects about 1 out of every 5,000 people but mostly African Americans. Since it basically has the body producing useless blood cells, it works the same on anyone who gets it.

No Sickle Cell is not like Leukemia... I am not sure why people assume that. I can tell you why Hematology (blood Disorders) and Oncology (Cancer) are together in the medical field as Hem/Onc. Leukemia was the first cancer discovered because Leukemia is a cancer of the blood they put it with blood disorders. SN: Hem/Onc is the only field of medicine where if you want to treat cancer you are forced into treating blood disorders, or vice vera.

Since the capacity of the blood to carry oxygen is lower with sickle cell anaemia, your whole body is effected. You get tired very quickly, and because of the anormal shape of the blood cells strokes are more likely because coagulation can happen more easily.

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Sickle Cell disease

A disease that involves misshaped cells that can easily cause blood clots.

there is no specific group of people can get this disease, but i can tell you that in some country you will find the majority of sick people accumulate in one region and that due to the marriage from the same place in this case the no. of sickle disease will increase in that particular area.

Sickle cell trait is an inherited blood disorder that affects 1 million to 3 million Americans and 8 to 10 percent of African Americans. Sickle cell trait can also affect Hispanics, South Asians, Caucasians from southern Europe, and people from Middle Eastern countries.

By running some blood-tests if you have symptoms that indicate you have the disease. Some of those symptoms are anemia, jaundice, pain in long bones, abdomen pain etc. One of those test is "sickle solubility test." If it is positive, you have sickle cell anemia, another one is electrophoresis.

Heterozygous induviduals pass the dominant and recessive alleles to offspring

Describe the effect that sickle cell anemia has on the sedimentation rate!

1 have o good hygiene

2 when brushing your teeth scrape your tongue gently too

3 eat healthy

4 don't sip too hot soup/liquid

5 don't put sharp objects in your mouth

6 don't lick dirty objects to avoid infection

7 avoid too spicy food

8 always gargle or rinse your mouth after eating

9 don't swallow inedible object esp chemicals

10 avoid tongue piercing as much as possible

Cannot carry normal levels of oxygen to cells :) *NovaNet*

Sickle cell disease is an inherited blood disorder that affects red blood cells.

The 11th pair of chromosomes contains a gene responsible for normal hemoglobin production. A mutation or error in this gene is what causes sickle cell disease.

The sickle cells can block the flow of blood through vessels resulting in lung tissue damage (acute chest syndrome), pain episodes (arms, legs, chest and abdomen), stroke and priapism (painful prolonged erection). It also causes damage to most organs including the spleen, kidneys and liver. Damage to the spleen makes sickle cell disease patients, especially young children, easily overwhelmed by certain bacterial infections. All The above mentiond causes will appeare if the patient not get proper medication

Yes, Sickle Cell-Anemia is a genetic condition that is passed down from one generation to the other.

Sickle Cell Anemia is Autosomal Recessive. It arises from a mutation on the beta-globin gene of chromosome 11.

Because Sickle Cell Anemia is an example of incomplete dominance, a person has the disease if they have two mutated beta-globin genes but only has the trait (is a carrier) if they have only one mutated beta-globin gene.

Hemoglobin molecules are mutated, thus giving the red blood cells an abnormal, rigid shape.

No. It is a generally found only in the African/ American community.

you should increase your water intake as much as you can to prevent dehydration and take pain killer in a crisis and take amoxil to prevent infection with supplemental folic acid to increase RBC production

and there is new drug called hydroxyurea which increase hemoglobin F which characterized by high affinity to oxygen which might prevent the crisis or make them milder...

Because individuals who inherit the gene from only one parent produce red blood cells which are distorted. This distortion makes the cells unpalatable to malaria parasites, without seriously harming the individual. This tends to protect against malaria and that protection causes selection for this allele. Individuals who get the sickle cell gene from both parents suffer serious distortion of the red blood cells. This protects against malaria, but also reduces the oxygen-carrying capacity of the red cells to a dangerous degree. This causes a disease called sickle-cell anaemia, which causes selection against the gene. In malarial regions a balance is established. When a population with sickle cell alleles moves to an area with effectively no malaria present, the sickle cell alleles are steadily selected against. This shifts the balance steadily towards low levels.

Sickle cell anemia is an inherited disease. People who have the disease inherit two copies of the sickle cell gene-one from each parent. The sickle cell gene causes the body to make abnormal hemoglobin. Hemoglobin is the iron-rich protein that gives blood its red color and carries oxygen from the lungs to the rest of the body. In sickle cell anemia, the hemoglobin sticks together when it delivers oxygen to the body's tissues. These clumps of hemoglobin are like liquid fibers. They cause the red blood cells to become stiff and shaped like a sickle, or "C." The sickled red blood cells tend to stick together and get caught in the blood vessels. (Other cells also may play a role in this process.) Two copies of the sickle cell gene are needed for the body to make the abnormal hemoglobin found in sickle cell anemia.

AR 40-501

Chapter 2

Physical Standards for Enlistment, Appointment, and Induction

2-4. Blood and blood-forming tissue diseases

a. Anemia. Current hereditary or acquired anemia, which has not been corrected with therapy before appointment or induction, is disqualifying. For the purposes of this regulation, anemia is defined as hemoglobin of less than 13.5 for males and less than 12 for females. The following ICD-9 codes are used for diagnosed anemia: hereditary hemolytic anemia (282), sickle cell disease (282.6), acquired hemolytic anemia (283), aplastic anemia (284), or unspecified anemias (285).

I have sickle cell anemia and I desire to join to military too. You can always ask the recruiter for more questions.

Priapism is caused by leukemia, sickle cell disease, spinal cord injury, a rare side effect of the anti-depressant trazodone (Desyrel) or an overdose of self-injected chemicals to treat impotence.