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What is the bioavailability of a drug?
Bioavailability of a drug is the amount of the drug that is available for use by the body after it has been metabolised by the liver.
What is bioavailability?
Bioavailability is the amount of drug which reaches the site of physiological activity after administration.
What is a bioequivalence?
A bioequivalent is a formulation of a drug which is equivalent to some other formulation in terms of bioavailability.
How route of administration drug can control bioavailability drug?
biovability of intral nasal route
Bio availabilty has a better feature when it gets dissolved or undissolved?
Bioavailability measures the amount of a drug (medicinal) or other substance which enters the blood. This depends on two types of factors: 1) The physical and chemical properties of the drug. If a drug is insoluble (ie does not dissolve) in the stomach or intestine it is unlikely to be absorbed into the blood, so its bioavailability will be low. If it is soluble it is more likely to be absorbed so its bioavailability will be high. 2) The route in which it is given. Direct injection into the blood gives 100% bioavailability. Taking a drug by mouth is likely to give less than 100% bioavailability. For more details see: http://www.merck.com/mmpe/sec20/ch303/ch303c.html
Can a drug which is 100 percent absorbed from GI tract have 100 percent bioavailability?
yes
How does chemical stability of the drugs in the gastrointestinal tact affect the bio-availability of the drugs?
Bioavailability is used to describe the fraction of an administered dose of unchanged drug that reaches the systemic circulation, so we need chemically stable drug in order to increase the chance of drug absorbance and thus increased bioavailability.
What is a bioenhancer?
A bioenhancer is a biological enhancer - any naturally-occurring compound which increases drug bioavailability.
What is the medical term meaning extent to which a drug or other substance becomes available to the body?
Bioavailability
What is bioenhancer?
A bioenhancer is a biological enhancer - any naturally-occurring compound which increases drug bioavailability.
What factors determine a drug's rate of metabolism?
How quickly a drug clears from the body is a function of its absorption, bioavailability, distribution, metabolism, and excretion properties.
Why is a pharmaceutical equivalent not necessarily therapeutically equivalent?
They can still have different bioavailability (the amount of drug that is delivered to the site of action and the rate at whcih it is available). Pharmacetical equivalents do not have to have the same release mechanisms, and can therefore affect their bioavailability.
