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It's not such a simple answer I'm afraid.
If you are asking how many people have 2 deficient genes for the production of Alpha-1 Antitrypsin in the liver (and other parts of the body) then the answer is between 1 in 2000 live Caucasian births to one in ever 10 or 20,000.
Right now in the USA and Canada there are roughly 10,000 identified alphas and estimates of another 90,000 undiagnosed or misdiagnosed.
It is the number one autosomal recessive genetic condition humans face.
As with many such conditions, having the deficiency is not a disease in and of itself. Being deficient simply means that you any or all of the skin, liver and/or lung diseases that can occur because of the deficiency.
Wiki User
∙ 12y ago
Wiki User
∙ 12y agoOver-all the life expectancy is about 54 years. However, that depends heavily on other factors.
For the lung disease whether the person smokes is a bigger factor in whether or not they get lung disease than the gene itself.
Whether or not the person has viral hepatitis appears to account for nearly all of the severe liver disease and mortality.
So it appears that what the gene really does is to make you more sensitive to the effects of smoking and viral hepatitis. If you avoid both the life expectancy is normal.
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How many Americans lack alpha-1-antitrypsin?
The number of Americans with this deficiency is relatively small, probably no greater than 70,000
How many people have alpha 1 antitrypsin deficiency?
It is thought that every 1:2000 Caucasian births results in someone who is genetically 'alpha-1 antitrypsin deficient'. This puts the potential deficient population in the US at about 100,000 even though only a fraction of that number has been identified. For more information go to the related link below.
Approximately how many people worldwide are thought to be affected by iron deficiency?
1.6 billion people
How many people have alpha 1?
It's not such a simple answer I'm afraid. If you are asking how many people have 2 deficient genes for the production of Alpha-1 Antitrypsin in the liver (and other parts of the body) then the answer is between 1 in 2000 live Caucasian births to one in ever 10 or 20,000. Right now in the USA and Canada there are roughly 10,000 identified alphas and estimates of another 90,000 undiagnosed or misdiagnosed. It is the number one autosomal recessive genetic condition humans face. As with many such conditions, having the deficiency is not a disease in and of itself. Being deficient simply means that you any or all of the skin, liver and/or lung diseases that can occur because of the deficiency.
How many causes of SCID are adenosine deaminase deficiency?
Adenosine deaminase deficiency (ADA). About 50% of SCID cases are of this type.
What are some Vitamin D deficiency symptoms?
There are many Vitamin D deficiency symptoms and here are the most common ones:ricketsosteoporosisobesityfatiguechronic backachecancersDiabetesHeart diseaseshyperparathyroidismdepression
Which of the following is caused by mineral deficiency A) beriberi B)goitre C)scurvy D)night blindness?
Beriberi is caused by thiamine (vitamin B1) deficiency Goitre can be caused by iodine deficiency - although there are other potential causes. Scurvy is caused by vitamin C deficiency Night blindness (Nyctalopia) can have many different causes - but one cause is vitamin A deficiency.
What is a example of a deficiency in the legacy environment?
Many costly interfaces
How many types of deficiency disease are there?
vitamin A,B ,and more
What are examples of a deficiency in the legacy environment?
Many costly interfaces
What is the Effect of mineral and vitamin deficiency on enzyme activity?
many vitamins and minerals play crucial roles in many metabolisms as coenzyme or cofactor. Deficiency of those lower the related-enzyme activity.
Why is it important to use iodized salt in food?
The ingestion of iodide prevents iodine deficiency. Worldwide, iodine deficiency affects about two billion people and is the leading preventable cause of mental retardation.[1] It also causes thyroidgland problems, including endemic goiter. In many countries, iodine deficiency is a major public health problem that can be cheaply addressed by iodisation of salt.
