when your blood doesn't clot properly then the chemical reactions wont be accurate and good and will cause homeostasis to fail which will cause the organism to die
The clinical answer would be yes, however there are many exceptions to the rule in the case of hemophilia. The trait for hemophilia is carried on the X chromosome and is often recessive. This being the case, since females have 2 X chromosomes, there is typically a dominant gene on their other X that corrects the disorder if one X carries the trait for hemophilia.
Males, having only one X chromosome (paired with a Y chromosome) an only express the traits on the one X that they have. This being the case, a male with the trait for hemophilia on his X chromosome must be affected by it.
In more recent years it has become understood that the trait for hemophilia is not as recessive as once thought. In many females the trait has shown incomplete or shared dominance with the otherwise normal gene. This often results in the female having low clotting factor levels and actually being considered a mild or moderate hemophiliac.
Hemophilia is passed down from mother to son. It is extremely
rare for a woman to have hemophilia. It is necessary, though, for
a woman to be a carrier of the disorder for her son to acquire this
disorder. Females have two X chromosomes whereas males only
have one. When a boy is born, he takes one X chromosome from
his mother and one Y chromosome from his father. Therefore, he
can only get hemophilia through his mother.
Example One:
Mother(Carrier)+Father(Non-Affected)=50% chance of their son
acquiring the disorder and 50% chance of their daughter being a
carrier.
Example Two:
Mother(Non-Affected)+Father(Hemophiliac)=All sons will be
non-affected and all daughters will be carriers.
No. There are several types of bleeding disorders. Hemophilia is a deficiency in clotting factor proteins VIII (Hemophilia A), IX (Hemophilia B), or XI (Hemophilia C). There are several other clotting factor proteins linked to coagulation, as well as the vonWillebrands protein, and platelet disorders. Hemophilia is simply the most widely recognized (by the general public) bleeding disorder. It is important to know that many other bleeding disorders exist, such as the platelet deficiency you are asking about.
Literally love of blood.
Congenital tendency to uncontrolled bleeding; usually affects males and is transmitted from mother to son.
It is a genetic disorder in which a per son's blood clots very slowly or not at all.
Hemophilia is a mutation of either of the genes that make factor VII or IX. Hemophilia A is a mutation of the F8 gene and Hemophilia B is the mutation of the F9 gene. Both of these mutations occur on the sex-linked X chromosome.
Hemophilia is passed down from mother to son. It is extremely
rare for a woman to have hemophilia. It is necessary, though, for
a woman to be a carrier of the disorder for her son to acquire this
disorder. Females have two X chromosomes whereas males only
have one. When a boy is born, he takes one X chromosome from
his mother and one Y chromosome from his father. Therefore, he
can only get hemophilia through his mother.
Example One:
Mother(Carrier)+Father(Non-Affected)=50% chance of their son
acquiring the disorder and 50% chance of their daughter being a
carrier.
Example Two:
Mother(Non-Affected)+Father(Hemophiliac)=All sons will be
non-affected and all daughters will be carriers.
It's important for society to know how scary hemophilia can be. Hemophilia is a blood clotting disorder in which it is hard to clot once bleeding has occurred. People that have hemophilia (mostly males) often lose a lot of blood and need donor blood. People in society need to know before they donate blood that their blood is clean (free of AIDS especially).
People that have hemophilia are limited to certain activities and need to be extremely careful every minute of every single day.
Since the gene for Hemophilia is carried on the X chromosome and males pass only their Y chromosome onto their sons, no their sons should not have hemophilia. Of course all daughters of a male with hemophilia will be carriers of the mutation since they with receive his X chromosome, not the Y.
The major signs and symptoms of hemophilia are excessive bleeding and easy bruising.
Excessive BleedingThe extent of bleeding depends on the type and severity of the hemophilia. Children who have mild hemophilia may not have symptoms unless they have excessive bleeding from a dental procedure, an accident, or surgery. Males who have severe hemophilia may bleed heavily after circumcision.Bleeding can occur on the body's surface (external bleeding) or inside the body (internal bleeding).
Signs of excessive external bleeding include:
Signs of internal bleeding include blood in the urine (from bleeding in the kidneys or bladder) and blood in the stool (from bleeding in the intestines or stomach).
Bleeding in the JointsBleeding in the knees, elbows, or other joints is another common form of internal bleeding in people who have hemophilia. This bleeding can occur without obvious injury.At first, the bleeding causes tightness in the joint with no real pain or any visible signs of bleeding. The joint then becomes swollen, hot to touch, and painful to bend.
Swelling continues as bleeding continues. Eventually, movement in the joint is temporarily lost. Pain can be severe. Joint bleeding that isn't quickly treated can permanently damage the joint.
Bleeding in the BrainInternal bleeding in the brain is a very serious complication of hemophilia that can happen after a simple bump on the head or a more serious injury. The signs and symptoms of bleeding in the brain include:There are no environmental factors that contribute to or worsen the disorder itself, however it can greatly impact the symptoms. As heat dilates blood vessels the temperature can influence the amount of bleeding that takes place after injury. Many people with hemophilia develop hemoarthritis which is arthritisthat results from bleeding into the joints. As anyone with arthritis can tell you, the climate can make a huge difference in the condition and its impact.
The gene that causes hemophilia is located on the X chromosome. A woman who gives birth to a child with hemophilia often has other male relatives who have hemophilia. Sometimes, a baby will be born with hemophilia when there is no known family history. This means the gene can be"hidden"( or passed down through several generations of female carriers without affecting any male members of the family) or the change in the X chromosome is new (a spontaneous mutation).
Transmitted by a dominant gene. If that gene is inherited from either parent, the offspring will develop HD. If the gene is NOT inherited, then the offspring will not have HD- AND cannot pass the gene to their offspring.
Hemophilia is actually the lacking of specific proteins in the blood. The liver normally produces these proteins (called clotting factors) but in people with hemophilia it does not function normally, either not producing or produces non funtioning versions of one or more of these clotting factor proteins
No. The disorder is genetic.
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No. Hemophilia is not curable at this time. However, it is treatable. Using blood products, artificial blood clotting factors and in some cases hormones that induce the production of clotting factors, hemophilia can be treated. Hemophiliacs still require careful medical monitoring, but it is fairly manageable today.
However, scientists are considering gene replacement therapy as a possible option in the future.
Yes, a person with Hemophilia can drink alcohol, however drinking in excess is not good for anyone. Alcohol itself does not interact with the actual medications taken (Clotting Factor Proteins) for hemophilia. Since alcohol can thin a person's blood, alcohol consumption can make a current bleeding issue worse. If there is no active bleed, alcohol should make little to no difference in that end of the hemophiliac's medical spectrum.
Other complications often found in some older hemophiliacs may include liver disease at which point alcohol definitely creates a larger problem and can speed up liver damage but this is not due to hemophilia itself.
In short, Alcohol in excess is not good for anyone, but hemophiliacs can drink alcohol if they are conscious of their own situation and are responsible about it.
Hemophilia is not contagious by any means, however it can be passed from parent to offspring in the way of genetics.
It can be. More so in the past. Treatment of hemophilia has come a long way. In parts of the world where treatment options are limited (normally due to costs and availability) many injuries can be fatal or result in amputation. So long as the hemophiliac has access to up to date treatments the likelihood of hemophilia being fatal is very small. Trauma to the head or major organs can still be life threatening though and must be taken seriously.
Depending on the definition of carrier you're using the answer is yes or no.
Definition 1: An individual with a genetically linked disorder whom, while showing no signs or symptoms of the disorder, can pass the genetic disorder to their children.
Answer:
In this case, the answer would be no. If a male has a genetic mutation for hemophilia, he would show the signs and symptoms. Since the trait is located on the X chromosome and males only have one X chromosome there would be no choice but to demonstrate that trait.
Definition 2: An individual with a genetic disorder whom can pass that disorder on to their children.
Answer:
In this case, the answer would be yes. Males will pass the genetic mutation on to their daughters but since they pass their Y chromosome on to their sons, not the X, males cannot pass the genes to their sons.
The gene for hemophilia is carried on the X chromosome. A male has one X and one Y. Since the trait is recessive it would be easier for a male to get a recssive allele, rather than a female get two recessive alleles.