Hemophilia

Hemophilia is an example of a genetic disorder that affects the body's ability to form blood clots, leading to excessive bleeding and bruising. It is caused by a deficiency in clotting factors, most commonly factor VIII or IX.

Hemophilia is caused by a deficiency of clotting factor VIII (hemophilia A) or clotting factor IX (hemophilia B).

Yes - there are dogs with hemophilia. German Shepards in Europe with hemophilia can be traced back to one dog: Canto von der Wienerau.

For more informationon hemophilia and dogs: http://mydogfluffy.com/faq.htm

Mice with hemophilia are used to research hemophilia medication and a cure for hemophilia.

It was in his genes. His mother Alexandra carried the disease and gave it to Alexei. Her mother gave the carrying Disease to her. Her own brother Frettie Died from hemophilia when he was three. He fell out of a window. A

No, hemophilia is not contagious. It is an inherited genetic disorder that affects the blood's ability to clot properly. It is passed down from parents to their children through genetic mutations on the X chromosome.

Hemophilia must be diagnosed through blood tests. Family history of bleeding disorders can help narrow the tests needed to make an accurate diagnosis. If hemophilia is known in the patient's history and a bleeding disorder is suspected, it is probably the same, both in severity and type. Actual diagnosis however should only be bade following appropriate blood tests.

A corrected human hemophilia gene would be considered medicine, as it is aimed at treating a genetic disorder in humans.

The father is the one who can pass the allele for hemophilia to a daughter. Hemophilia is a recessive X-linked disorder, so the daughter would need to inherit the hemophilia allele from her father.

Hemophilia is caused by mutations in genes located on the X chromosome that are responsible for producing blood clotting factors. In particular, mutations in the genes for factor VIII or factor IX can lead to hemophilia A or hemophilia B, respectively. These mutations result in deficient or dysfunctional clotting factors, leading to impaired blood clotting and increased bleeding tendencies.

Hemophilia is inherited in an X-linked recessive pattern, meaning it primarily affects males who inherit the affected X chromosome from their carrier mother. Sickle cell anemia is inherited in an autosomal recessive pattern, meaning both parents must pass on a mutated gene for the child to develop the condition regardless of gender.

impairs the blood's ability to clot properly due to missing or reduced levels of clotting factors, leading to prolonged bleeding episodes. It is inherited in an X-linked recessive pattern, primarily affecting males. Treatment involves replacement of the missing clotting factors through infusions.

Hemophilia is most often caused by mutations in the F8 gene, located on the X chromosome. This gene provides instructions for making a protein called factor VIII, which is essential for blood clotting. Mutations in the F8 gene can result in reduced or absent levels of factor VIII, leading to the characteristic bleeding problems seen in hemophilia.

The gene for hemophilia is found on the 'X' human chromosome. However it is a recessive gene so if a woman (who has two 'XX' chromosomes) has one bad 'X' and one good 'X' she will not have hemophilia but will be a carrier .

If she has female children and their father is not a hemophiliac, then half of her daughters may carry the bad 'X' chromosome but non will manifest the disease.

However, if her children are male then her sons will have an 'X' chromosome inherited from her and a 'Y' chromosome inherited form the father and there is a 50% chance that the 'X' chromosome inherited will be the bad one. If the son inherits the bad 'X' he will be a hemophiliac and if he lives to father any daughters then all these daughters will be hemophilia carriers (because they must inherit his (bad) 'X' chromosome).

It is possible for a woman to manifest hemophilia if the mother is a carrier and the father is a hemophiliac. In this case it is possible for a daughter to inherit the bad 'X' from the father and the mother's bad 'X' giving the daughter two bad 'X' chromosomes.

Yes, royal hemophilia, also known as the "Royal disease," is a hereditary bleeding disorder caused by a mutation in the gene responsible for producing a blood clotting protein. It is inherited on the X chromosome. Because males have only one X chromosome, they are more likely to express the hemophilia trait if they inherit the mutated gene.

Hemophilia is passed down from mother to son. It is extremely

rare for a woman to have hemophilia. It is necessary, though, for

a woman to be a carrier of the disorder for her son to acquire this

disorder. Females have two X chromosomes whereas males only

have one. When a boy is born, he takes one X chromosome from

his mother and one Y chromosome from his father. Therefore, he

can only get hemophilia through his mother.

Example One:

Mother(Carrier)+Father(Non-Affected)=50% chance of their son

acquiring the disorder and 50% chance of their daughter being a

carrier.

Example Two:

Mother(Non-Affected)+Father(Hemophiliac)=All sons will be

non-affected and all daughters will be carriers.

Hemophilia B is called the Christmas disease because it was first discovered in a young boy named Stephen Christmas who experienced severe bleeding after a minor injury on Christmas day in 1952. This incident led to the identification of hemophilia B as a distinct type of hemophilia caused by a deficiency in clotting factor IX.

Her father has to have hemophilia as well, and the mother is a carrier or also has hemophilia. So if we pretend that the hemophilia gene is "x", you need to have "xx" to have hemophilia. The father must have the genotype "Yx" and the mother has the have "Xx" or "xx".

Yes, hemophilia can be life-threatening if not managed properly. Excessive bleeding, especially internally or in the brain, can lead to serious complications or death. Regular medical supervision and treatment are essential for individuals with hemophilia to prevent severe bleeding episodes.

Traditional Hemophilia is present from birth and throughout the individual's life. This is because the disorder is genetically linked and genetics are pretty much set at the time of conception.

Acquired Hemophilia, which is much more rare, can begin at pretty much any stage of an individual's life. While being more common in older people than younger, any person on certain medications, people with liver disease, and a handful of other situations can develop acquired hemophilia. (Acquired hemophilia is not inherited.)

Hemophilia normally refers to a genetic disorder that can be either inherited or the result of a spontaneous mutation. Since the genetic form of hemophilia is linked to a mutation on the X chromosome, males typically show the full symptoms while females with the mutation typically have somewhat mitigated symptoms or none at all.

While the majority of the cases of genetic hemophilia are inherited, meaning that the genes were passed down from the the parents, approximately 1/3 of the cases are spontaneous mutations. The mutation occurs at conception, meaning that all genetic forms basically take effect at birth.

Acquired hemophilia is a result of some other influence such as liver damage or specific medications. This form of hemophilia is neither inherited nor genetic.

In short, technically anyone can get hemophilia. Genetic hemophilia is present at birth, and it tends to impact the health of males more than females, but can affect females too.

*disclaimer - i am by no means a doctor and my advice is not professional lol

but hemophilia is a genetic disorder with the blood, which would lead me to believe that if you have hemophilia, it would be evident from birth

It is due to two factors. One is that these traits are coded on the x-chromosome, of which women have two, men only one (since it is paired with a y-chromosome in men). The other factor is that the two traits are both recessive, that is they are suppressed in the presence of the dominant, healthy allele. In men there is no other x-chromosome, which could provide a healthy allele to counteract the effect of the mutant alleles, therefore these disorders occur more frequently.

However, due to mosaicism, and x-chromosome inactivation (Barr-body formation), women who carry the color-blind x-chromosome have color-blind patches in their retinas, or may even be nearly completely color-blind in one eye.

Well since Hemophilia is an inherited disorder where the proteins needed to form blood clots are missing or reduced, every cut or injury effects a person with Hemophilia. If depending on whether your Hemophilia is severe, mild, or moderate your cognitive ability is reduced, to prevent scraps and cuts. Hemophilia is treatable through plasma donations and certain medicine, however you have to always be cautious.

Almost certainly no. Hemophilia cannot be passed from father to son. There is a very slight chance (almost incalculable) that a spontaneous mutation can take place and thus make the son turn out to be a hemophiliac himself. Using the the best guess from the CDC, nearly 1/3 of hemophiliacs are the result of a random mutation. the statistic of 1 in 5000 male births is also a CDC statistic, this would imply that the son would have approximately a 1 in 15,000 chance of having hemophilia and his father's genetics would have nothing to do with it.

Men and women each have 23 pairs of chromosomes. Women have two X chromosomes; men have one X and one Y chromosome. Hemophilia is an X-linked genetic disorder, which means that it's passed from mother to son on the X chromosome. If the mother carries the gene for hemophilia on one of her X chromosomes, each of her sons will have a 50% chance of having hemophilia.

Hemophilia affects mostly boys, although it's very rare: Only about 1 in every 5,000 boys is born with it. The disease can affect people of any race or nationality.