Hemophilia

Hemophilia can't be cured by chemicals cuz it is a structural fault in genes that needs some other technique to be able to function like normal cells. Is hemophilia curable at this time? The answer to that question is NO but hemophilia would be curable in future as genetics is in its early stages.

Hemophilia is passed down from mother to son. It is extremely

rare for a woman to have hemophilia. It is necessary, though, for

a woman to be a carrier of the disorder for her son to acquire this

disorder. Females have two X chromosomes whereas males only

have one. When a boy is born, he takes one X chromosome from

his mother and one Y chromosome from his father. Therefore, he

can only get hemophilia through his mother.

Example One:

Mother(Carrier)+Father(Non-Affected)=50% chance of their son

acquiring the disorder and 50% chance of their daughter being a

carrier.

Example Two:

Mother(Non-Affected)+Father(Hemophiliac)=All sons will be

non-affected and all daughters will be carriers.

First of all, there is no such thing as hemophilia C. Second,

Type A:

A mutation in the

factor VIII gene.

Type B:

A mutation in the IX

gene.

Both of these genes are need to help clot the blood and close wounds(scabbing).

Hemophilia is not a cold that one gets over and can recover from. It is a genetic condition resulting in either poor production of a clotting factor protein or no production at all.

There are ways to stop some of the symptoms of hemophilia, like factor replacement therapy. This therapy involves injecting the missing clotting factor protein directly into the individual's veins and can be utilized in basically 3 different ways. Since the proteins break down pretty quickly, the frequency of iv infusions depends on the method of therapy. Some individuals infuse routinely (often either 3 times per week or every other day) which prevents most bleeds from occurring as well as preventing joint damage. This form of therapy is called prophylaxis. Another type of prophylaxis involves treating prior to physical activities that may cause a problem. The 3rd way replacement therapy can be used is solely treating once a problem has arisen.

Another known way to stop the symptoms of hemophilia is by giving the individual a liver transplant. Since the liver has the donor's genetics and not the hemophiliac's it wil continue to produce the clotting factor proteins as normal.

As far as the genetics involved with hemophilia are concerned, there is no real way to prevent this from occurring. Many cases are the result of the genetics being passed down through the family tree. In these cases, abstinence may in part prevent some cases. The problem with this scenario is that many of the females who carry the trait are unaware that they have it. Secondly, as many as 1/3 of the cases of hemophilia are thought to be the result of a random mutation. If we were to stop mutations from taking place we would be virtually stopping the evolutionary process.

Common side effects of hemophilia include excessive bleeding, bruising easily, joint pain and swelling due to internal bleeding, and an increased risk of developing hematomas. Patients may also experience complications from prolonged bleeding, such as anemia or damage to internal organs. Additionally, individuals with hemophilia may be at higher risk for developing infections due to frequent injections of clotting factor concentrates.

If both parents have x-linked hemophilia, the father's genotype would be XhY and the mother's genotype would be XhXh, which is astronomically rare. If this did happen, all of their children would inherit x-linked hemophilia.

Hemophilia is passed down from mother to son. It is extremely

rare for a woman to have hemophilia. It is necessary, though, for

a woman to be a carrier of the disorder for her son to acquire this

disorder. Females have two X chromosomes whereas males only

have one. When a boy is born, he takes one X chromosome from

his mother and one Y chromosome from his father. Therefore, he

can only get hemophilia through his mother.

Example One:

Mother(Carrier)+Father(Non-Affected)=50% chance of their son

acquiring the disorder and 50% chance of their daughter being a

carrier.

Example Two:

Mother(Non-Affected)+Father(Hemophiliac)=All sons will be

non-affected and all daughters will be carriers.

Color blindness is a sex-linked genetic disorder. The reason that it is more prevalent in males is because the disorder is linked the the X-chromasome. If a male inherits an X chromosome that is defective, then they will be color blind. However, a female has two X chromosomes which means she can receive a defective chromosome and only be a carrier of the mutation. If she receives two defective x chromosomes, she will be colorblind.

The woman's father being unaffected means that he does not carry the gene for hemophilia on his X chromosome. Therefore, the woman does not have the gene and cannot pass it on to her son. Her son will not inherit hemophilia from his uncle.

It depends on the severity, the life style, and the level of medical care.

Males can live into their seventies, but the average is much lower ... mid-thirties is common.

Females (very rare) almost never live past their teens.

Hemophilia was first recognized as a hereditary bleeding disorder in the 1800s when doctors noticed that certain royal families had members with symptoms of excessive bleeding. In 1803, Dr. John Conrad Otto identified hemophilia as a distinct medical condition. Later, in 1952, researchers discovered that hemophilia is caused by a deficiency in clotting factors in the blood.

Mutations in the F8 and F9 genes cause hemophilia. Changes in the F8 gene are responsible for hemophilia A, while mutations in the F9 gene cause hemophilia B. The F8 gene provides instructions for making a protein called coagulation factor VIII. A related protein, coagulation factor IX, is produced from the F9 gene. Coagulation factors are proteins that work together in the clotting process. After an injury, blood clots protect the body by sealing off damaged blood vessels and preventing further blood loss. Mutations in the F8 or F9 gene lead to the production of an abnormal version of coagulation factor VIII or coagulation factor IX. The altered protein cannot participate effectively in the blood clotting process and, in some cases, the protein does not work at all. A shortage of either protein prevents clots from forming properly in response to injury. These problems with blood clotting lead to excessive bleeding that can be difficult to control. Some mutations almost completely eliminate the activity of coagulation factor VIII or coagulation factor IX, resulting in severe hemophilia. Other mutations reduce but do not eliminate the activity of one of these proteins, which usually causes mild or moderate hemophilia. The other, rare form of this condition, acquired hemophilia, results when the body makes specialized proteins called autoantibodies that attack and disable coagulation factor VIII. The production of autoantibodies is sometimes associated with pregnancy, immune system disorders, cancer, or allergic reactions to certain drugs. In about half of cases, the cause of acquired hemophilia is unknown. Read more about the F8 and F9 genes. Hemophilia A and hemophilia B are inherited in an X-linked recessive pattern. A condition is considered X-linked if the mutated gene that causes the disorder is located on the X chromosome, one of the two sex chromosomes. In males (who have only one X chromosome), one altered copy of the gene in each cell is sufficient to cause the condition. In females (who have two X chromosomes), a mutation must be present in both copies of the gene to cause the disorder. Males are affected by X-linked recessive disorders much more frequently than females. A striking characteristic of X-linked inheritance is that fathers cannot pass X-linked traits to their sons. In X-linked recessive inheritance, a female with one altered copy of the gene in each cell is called a carrier. She can pass on the altered gene to her children, but usually does not experience signs and symptoms of the disorder. In about 10 percent of cases, however, females who carry one altered copy of the F8 or F9 gene will experience mild problems with bleeding. From: http://ghr.nlm.nih.gov/condition=hemophilia

Because hemophilia is a disease linked to a recessive gene on the X-chromosome, females have another X-chromosome to block out the diseased one. However, males have only one X-chromosome, so they are more often subject to hemophilia.

I believe it is a issue of the state of the soul. The refusal to be repentant to God and others they have harmed feeds the beast that grows in the N's mind and heart. They are empty and void of anything but love for self. Even the love they have for their children or mate is nothing more than a supply source. This is not a mental disorder, it is a soul disorder that can only be helped by the N repenting and allowing God to change them. Since the N must admit fault and set God above them , salvation is almost impossible unless God brings them to a place where he is all they have left. In order to help this person, you must set them free, pray for them and then move on with your life. Even if this person seems to have made a change, it may well be short lived because the temptation to exhault themself above you will be there every moment they live. It is a long , painful recovery and if you are reading this and have came to this site for help, you will not be the one that can help the person recover. It will open old wounds for both of you. Move on ..

Hemophilia is sex linked. Males inherit from their mother, daughters are carriers if the defective gene is inherited from one of either parent. A female must inherit two copies of the defective allele to have hemophilia .

yes hemophilia can be detected before birth

Males.

No it is not. Queen Victoria gave it two two daughters and a son. Because the son that ruled after her, Edward VII, was free of the disease it is highly unlikley that it would pop up in the present royal family. It could have been different though. Queen Victoria wanted her granddaughter Alix (Empress Alexandra) to marry Edward's son. If this marriage had taken place then hemophilia could have been introduced back into the blood line.

Hemophilia is passed down from mother to son. It is extremely

rare for a woman to have hemophilia. It is necessary, though, for

a woman to be a carrier of the disorder for her son to acquire this

disorder. Females have two X chromosomes whereas males only

have one. When a boy is born, he takes one X chromosome from

his mother and one Y chromosome from his father. Therefore, he

can only get hemophilia through his mother.

Example One:

Mother(Carrier)+Father(Non-Affected)=50% chance of their son

acquiring the disorder and 50% chance of their daughter being a

carrier.

Example Two:

Mother(Non-Affected)+Father(Hemophiliac)=All sons will be

non-affected and all daughters will be carriers.

Everyday life for hemophiliacs, expecially children, can be extremely difficult because they are unable to participate in all the activities they may want to. For example, it would be difficult for a hemophiliac to play hocky or be on the wrestling team because the injuries they may obtain could become severe. Although there are some holdbacks associated with hemophilia, not everything is out of the question. Hemophiliacs can still be active. They can participate in such sports as swimming or golf.

People should come to realize that hemophiliacs are living with a rare disease and they probably they already feel different, so why make them feel even more insecure by believing that they are inable to have "fun" and therefore reject their friendship?

Hemophilia is passed down from mother to son. It is extremely

rare for a woman to have hemophilia. It is necessary, though, for

a woman to be a carrier of the disorder for her son to acquire this

disorder. Females have two X chromosomes whereas males only

have one. When a boy is born, he takes one X chromosome from

his mother and one Y chromosome from his father. Therefore, he

can only get hemophilia through his mother.

Example One:

Mother(Carrier)+Father(Non-Affected)=50% chance of their son

acquiring the disorder and 50% chance of their daughter being a

carrier.

Example Two:

Mother(Non-Affected)+Father(Hemophiliac)=All sons will be

non-affected and all daughters will be carriers.

Haemophilia is an hereditary disease that affects the coagulation factors, they suffer mutations and don't work properly. This leaves the person vulnerable to hemorrhage, injuries take a lot longer to heal and may suffer of spontaneous bleeding (be it a simple nosebleed or severe gastrointestinal bleeding). Chronic hemorrahges cause anemia and iron deficit, and the loss of blood volume lowers the arterial pressure and causes tachycardia. In the worst case, a person can bleed to death with realtively minor injuries.

recessive sex-linked, X chromosome disorders, haemophilia is more likely to occur in males than females.

No, Hemophilia does not discriminate on age, race or religion.

Hemophilia is a genetic disorder (with the exception of acquired hemophilia) and therefore an individual has hemophilia from the the time they are born until they die.

There is one very rare form of genetic hemophilia where the individual "outgrows" the disorder. In fact, the hormonal changes that take place during puberty increase the production of the clotting proteins to a point above the 50% cut off for being considered as having hemophilia. the genetics however, remain the same.

It can cause severe bleeding or hemorrhage which will cause respiratory distress.