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Ibuprofen

Questions about Ibuprofen, also known by the names Brufen, Nurofen, Advil, and Motrin.

1,563 Questions

How long should it take to get an answer on a voluntary dismissal of a Chapter 7 bankruptcy?

Normally takes a week or so. It depends on if the Judge orders a hearing (which some do, some don't).

If there is a hearing, normally a few days later there will be an order to dismiss.

Your daughter took 600mg of Ibuprofen for a sore throat instead of relieving the pain she developed a fever of 102 and a bad headache?

Sounds like the flu, or another infectious process. Try Tylenol, alternating with the Ibuprofen. If fever not resolving, stiff neck, continued severe headache, take to the doctor.

Why does my stomach feel empty when taking Fruta Plenta?

Fruta Plenta speeds up your metabolism, which also means that you use up food faster.

Fruta Planta has been recalled by the FDA. It contained unmarked ingredients that had been previously banned in the United States. There have been cardiac events and death reported with this supplement. The FDA has advised to stop taking it right away. See the related question for more information and links.

How do you get Motrin to work?

You take 400 to 600 mg every 8 hours.

Motrin (ibuprofen) is good for mild to moderate pain - it's not going to work as well for something severe like a broken bone or other severe injury. If 600mg of ibuprofen isn't working for your pain, it's time to see a doctor and get some prescription strength pain reliever.

What can I do when taking medicine on empty stomach I took it on an empty stomach by a mistake?

Eat something immediately and drink some water. That is all you can do, but don't worry about it too much. It may just mean it will cause stomachache or that it wasn't absorbed as well as it could have been.

What is cox1 and cox2 and cox3?

Cox1, Cox2, and Cox3 refer to different isoforms of cyclooxygenase enzymes, which are involved in the conversion of arachidonic acid to prostaglandins, compounds that mediate inflammation and pain. Cox1 (cyclooxygenase-1) is constitutively expressed and plays a key role in maintaining normal physiological functions, such as gastric protection and platelet aggregation. Cox2 (cyclooxygenase-2) is inducible and associated with inflammation and pain, making it a target for anti-inflammatory drugs. Cox3 is a less well-defined isoform, primarily studied in the context of the central nervous system, and is thought to be involved in pain perception but is less understood compared to Cox1 and Cox2.

Are 3 200mg the same as 600mg?

Yes, (3) 200 mg of Ibuprofen are the same as 600 mg.

How is Advil supplied?

Ibuprofen was initially introduced as a prescription NSAID used for such conditions as rheumatoid arthritis, in 1969 in the UK and 1974 in the US. Ibuprofen became available without a prescription in the US in 1984 under the name "Advil" and in the UK under the name Nurofen.

Timeline

1969 - Introduced in the US

When ibuprofen was introduced in the United States in 1974, the recommended dose there was 1200-3200 mg/day. This is three times the current recommended dose. The use became widespread and it was confirmed by the FDA as one of the safest of the non-steroidal anti-inflammatory drugs (NSAIDs) - However, concerns about side effects to the liver and stomach had been mounting for some time. During this time the official mascot of the Advil brand, Advil Aaron was introduced. He has since become a symbol for the brand.

1980s - Nurofen and Advil launched

Ibuprofen's safety record remained high with problems only being related to overdosing. The product was "Fast Tracked" from prescription to OTC (over the counter) status by the FDA. It became available in the UK in 1983 under the brand name Nurofen TM and in the United States in 1984 under the brand name Advil TM). Anyone could buy it without a prescription for the treatment of headaches, dental pain, migraine and menstrual pain. It is estimated that by 1985 over 100 million people had been treated with ibuprofen in more than 120 countries.

1984 - Need for Mass Production

As sales increased Whitehall Labs the US distributor of Advil quickly realized that Boots (the original manufacturer) could not keep up with demand. Boots was essentially making all the product manually in a mostly hand operation. Michael Dryden of the Whitehall R&D staff was assigned to form a team and create an automated manufacturing process ASAP. Dryden hired Guido Melenger, the head of a small pharma scale-up firm, to come up with an automated process. After three years of work, a team from Whitehall concluded that Melenger would be unable to complete the task and feared his company was about to go out of business. Whitehall then formed an internal team consisting of Dryden, Webb Crew (to develop software) and George Van Parys (to develop the machinery). The first prototype machine was produced in late 1986, with the the first production operation of units in late 1987.

1988 - Mega Sales = Mega Production

After obtaining full FDA approval for the first installation in Hammonton, NJ the task turned to improving the design of the machinery and increasing capacity. The same team worked on an improved design with major work being done by Van Parys on system design and efficiency. At the same time, Van Parys was designing and building a massive facility in Puerto Rico along with Steve Bennett, who was the construction manager of the site, to manufacture the product on a massive scale. This effort allowed for a second design and installation in Guayama, PR of an initial 20 new systems. Each system now produced 540,000 tablets every 9 hours or ~ 1,080,000 tablets per day per system. This gave Whitehall the ability to produce 32,400,000 tablets per day.

1996 - Hammonton, NJ Plant Closes

The now Whitehall-Robbins closed the Hammonton manufacturing facility in 1996, moving its 10 production units to Rouses Point, NY. This move was short lived and the units ended up in Guayama, PR in 2004. Continued to today this facility is the only production manufacturing operation for Advil in the US, although other Wyeth facilities package the product.

How many tablets of Peptibismal for age 9?

Do not give a 9 year old Peptobismol. It is a salicylate and shouldn't be given to children under 12 due to the risk of Rye's Syndrome.

How long do you have to wait before taking baby mice away from their mother before they start reproducing with each other?

At six weeks of age is the earliest you can separate babies from their mother successfully. However, if at all possible I would suggest waiting at least 8-12 weeks especially, if you are not clear on the actual age of the babies...

Actually, mice can reproduce at 4 weeks of age, so it's best to separate them at 3-4 weeks of age. If you have any doubts, if your baby mice are trying to eat solid foods, you should be able to separate them in a day or two.

What happens if you take 7 Advils?

That would be an overdose.

An overdose of Advil can cause you to become nauseous and vomit as well as causing stomach pain. Other symptoms can include drowsiness or coma and the vomiting of blood or the passing of bloody stools.

You should get emergency medical help if you think you have taken too much Advil.

You should tell the phone operator what medication was taken and how much as well as taking the packaging and any remaining tablets or capsules with you to the hospital as this can help the medical staff choose the correct treatment more quickly.

What is better for bleeding stomach uclers Tylenol or advil?

If one is having a bleeding ulcer it is advised not to take ANY NSAIDs ;NON STEROIDAL ANTI INFLAMMATORY...ie: Advil.

YOU also AVOID ASPIRIN as it causes a thinning of the blood.

You don't want to bleed to death through your stomach....do you?

If one is having bleeding it is advised to seek direct counsel from your care provider for what medication is best suited to your situation.

Yet is is standard medical protocol to avoid all NSAIDS with internal bleeding due to the mechanism of the NSAIDS being in the stomach and the COX2 enzyme.

How much Ibuprofen will equal Vicodin?

They are two different classes of medications, and there is no equivalent dosage.