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Anemia
This category is for questions about the lack of red blood cells or hemoglobin called anemia: its symptoms, causes, and treatment.
936 Questions
Can minor thalassemia carrier and alpha marry?
Yes, A "carrier" of alpha thalassemia and of beta thalassemia can marry, but not to someone with any hemoglobinopathy.
Prof. Kornfeld Pal
How deadly is hemolytic anemia in dogs?
Most definitely. The veterinary research shows about 50/50 chance. Survival odds are better if the dog survives the first few days.
Who does Sickle Cell Anemia effect?
Sickle-cell disease, usually presenting in childhood, occurs more commonly in people (or their descendants) from parts of tropical and sub-tropical regions where malaria is or was common. The prevalence of the disease in the United States is approximately 1 in 5,000, mostly affecting Americans of Sub-Saharan African descent. In simplified terms usually black people.
Is sickle cell anemia congenital?
Sickle-cell is inherited from parents just as physical traits. People with the disease are SS type and show the anemia. Others can carry the trait (Ss). They are able to fight off malaria. Since this type (Ss) is important in areas with many malaria cases, this is protective.
What are the causes of this disease and how is it transmitted sickle cell anemia?
it's caused by a mutation in the hemoglobin gene(a weird change that's basically in the red blood cell)disease is a group of genetic dis orders caused by sickle hemolobin(hgb s or hb s(
Common causes of microcytic hypochromic anemia?
It is important to note that sickle-cell anemia comes in two forms. The homozygous sickle-cell anemia and the heterozygous sickle-cell trait. The difference between the two is that sickle-cell anemia has a high rate death rate at a young age (20~), and the sickle-cell trait is nearly asymptomatic.
In regions such as North America, sickle-cell anemia would be selected against and would eventually leave the gene pool. The sickle-cell trait on the other hand, has little effect on the fitness of the organism, and as such will remain in the gene pool.
In malaria endemic regions such as sub-Sahara Africa, sickle-cell anemia provides very high levels of immunity to malaria and the sickle-cell trait provides a slightly lesser level of immunity. Both forms of sickle-cell will increase the organisms fitness and as such, it will remain in the gene pool. Further on, the sickle-cell trait has greater fitness than sickle-cell anemia, hence, the sickle-cell trait will be selected as the fittest allele.
If s is the sickle-cell allele and S is a normal allele;
The relative fitness in malaria endemic regions;
Ss > ss > SS
Sickle-cell trait > Sickle-cell anemia > Normal
The relative fitness in non-malaria endemic regions;
SS > Ss > ss
Normal > Sickle-cell trait > Sickle-cell anemia
What type of mutation causes sickle cell anemia substitution deletion insertion mutagen?
The type of mutation that causes a defect in the gene (causing sickle cell anaemia) is a substitution mutation.
A single nucleotide substitution (A to T) in the β-globin gene causes the amino acid valine to replace glutamic acid. This changes the resulting protein, causing a haemoglobin with an abnormal shape to be created.
it is used in making tables chairs and many other handy things
like wiring and piping (not like icing )
the sickle trait possess a resistance to the infection of malaria.
A CBC, or complete blood count, is a clinical procedure that can aid in the diagnosis of leukemia and anemia. The peripheral blood smear can also be helpful in diagnosis.
What part of the body would pernicious anemia occur in?
Pernicious Anemia has to do with your red blood cells lacking a strong count because of a great vitamin B12 deficiency, either some through some illness, infection or other cause that makes your stomach to be unable to absorb the necessary about of B12 from your food. So the part of the body this has to do with is your circulatory system, which in turn affects everything.
How do you write a conclusion on sickle cell eassy?
Write a summary of the main ideas you covered in the essay.
Explain the defect in the protein of Sickle-cell disease?
The defect is that hemoglobin (the protein) elongates. Instead of being circular, it acquires a crescent shape. With this shape, its harder for it to absorb and release oxygen. Also, when the blood cell reaches the capillaries, it can't fit through as well as normal blood cells can, which is why Sickle-Cell is painful.
If you have Thalassemia major but your boyfriend is not a carrier then the child will be born a healthy carrier (thalassemia minor) but shouldn't need blood transfusions. If your boyfriend is a carrier then you would have a 50% chance of having a child with thalassemia major like you do.
What is the rate of prevalence of iron deficiency anemia in India?
prevaalence of anemia in India in the year 2010
Role of heamodialysis in anemia of chronic renal failure?
chronic renal failure results in increased level of uric acid which inturn decrease life span of red blood cells causes anemia.Dialysis decrease uric acid level so increase life span of red blood cells
Is aplastic anemia considered cancer?
No. Cancer by definition entails growth. A.A. is a destruction of the stem cells that produce blood. (Both may require the same treatment of a bone marrow transplant)
Why hepatomegaly occurs in thalassemia?
Hepatomegaly in thalassemia occures as aresult of engorgement of hepatic paranchymal and phagocytic cells with hemosiderin deposits.
Definition.---An insufficient amount of blood circulating in the capillaries.
Etiology.---This may be due to general or local causes. Thus cerebral anemia may attend the general anemia coming from a severe hemorrhage or from profuse diarrhea, or from pernicious anemia, leukemia, and various cachexias, or it may be due to the accumulation of a large quantity of blood in the peritoneal cavity following the removal of ascitic fluid. A more serious condition would be anemia due to aortic stenosis. Among local causes may be mentioned obliterative endarteritis, compression of the brain from tumors, or a partial destruction of the circle of Willis.
Pathology.---The puncta vasculosa are so lessened many times as to escape detection, while there may be an increase in the cerebro-spinal fluid. The gray matter assumes a characteristic pallor.
Symptoms.---These are due to profuse, exhausting, diarrheal discharges, and, especially where due to hemorrhage, the symptoms are characteristic; there is dizziness, faintness, pallor of face, ringing in the ears, confusion of ideas, and marked dyspnea, and frequently terminating in a "dead faint." Where the anemia is sudden and intense, the syncopal attack may terminate fatally.
Where the anemia is more chronic in character, there is pallor of face, the skin is cool, and the pulse is feeble and irritable. The patient is listless and stupid, though we may meet cases with general irritability. There is a dull headache, vertigo, buzzing in the ears, spots before the eyes, and weakness of the muscles.
The hydrocephaloid symptoms, occurring in young children, so named by Marshal Hall, are pallor, dullness, contracted pupils, and depressed fontanels.
Treatment.---This will depend upon the cause giving rise to it. Where the attack is acute and sudden, the patient should be placed in the recumbent position, with the head depressed. A diffuse stimulant, like ammonium carbonate, gives prompt results. In severe cases, where there has been excessive hemorrhage, a subcutaneous injection of normal saline solution should be used. In the more chronic form, and when secondary, the treatment suggested for general anemia will be followed with nourishing food and gentle exercise in the open air.
