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Hemophilia

Hemophilia is a rare bleeding disorder characterized by abnormal blood clotting. The most common signs of hemophilia are easy bruising and too much bleeding. People suffering from hemophilia have less or no clotting factor.

500 Questions

Does a human offspring inherit hemophilia from the mother or father?

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Asked by Wiki User

Hemophilia is sex linked. Males inherit from their mother, daughters are carriers if the defective gene is inherited from one of either parent. A female must inherit two copies of the defective allele to have hemophilia .

Can hemophilia be detected in the child before birth?

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Asked by Wiki User

yes hemophilia can be detected before birth

Why is hemophilia a common disease in royal families?

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Asked by Wiki User

No it is not. Queen Victoria gave it two two daughters and a son. Because the son that ruled after her, Edward VII, was free of the disease it is highly unlikley that it would pop up in the present royal family. It could have been different though. Queen Victoria wanted her granddaughter Alix (Empress Alexandra) to marry Edward's son. If this marriage had taken place then hemophilia could have been introduced back into the blood line.

What are the chances for a baby to be born with hemophilia?

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Hemophilia is passed down from mother to son. It is extremely

rare for a woman to have hemophilia. It is necessary, though, for

a woman to be a carrier of the disorder for her son to acquire this

disorder. Females have two X chromosomes whereas males only

have one. When a boy is born, he takes one X chromosome from

his mother and one Y chromosome from his father. Therefore, he

can only get hemophilia through his mother.

Example One:

Mother(Carrier)+Father(Non-Affected)=50% chance of their son

acquiring the disorder and 50% chance of their daughter being a

carrier.

Example Two:

Mother(Non-Affected)+Father(Hemophiliac)=All sons will be

non-affected and all daughters will be carriers.

What limitations does a person have if they have hemophilia?

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Asked by Wiki User

Everyday life for hemophiliacs, expecially children, can be extremely difficult because they are unable to participate in all the activities they may want to. For example, it would be difficult for a hemophiliac to play hocky or be on the wrestling team because the injuries they may obtain could become severe. Although there are some holdbacks associated with hemophilia, not everything is out of the question. Hemophiliacs can still be active. They can participate in such sports as swimming or golf.

People should come to realize that hemophiliacs are living with a rare disease and they probably they already feel different, so why make them feel even more insecure by believing that they are inable to have "fun" and therefore reject their friendship?

If you have hemophilia what are the chances of giving it to your kids?

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Asked by Wiki User

Hemophilia is passed down from mother to son. It is extremely

rare for a woman to have hemophilia. It is necessary, though, for

a woman to be a carrier of the disorder for her son to acquire this

disorder. Females have two X chromosomes whereas males only

have one. When a boy is born, he takes one X chromosome from

his mother and one Y chromosome from his father. Therefore, he

can only get hemophilia through his mother.

Example One:

Mother(Carrier)+Father(Non-Affected)=50% chance of their son

acquiring the disorder and 50% chance of their daughter being a

carrier.

Example Two:

Mother(Non-Affected)+Father(Hemophiliac)=All sons will be

non-affected and all daughters will be carriers.

How does hemophilia affect the circulatory system?

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Asked by Wiki User

Haemophilia is an hereditary disease that affects the coagulation factors, they suffer mutations and don't work properly. This leaves the person vulnerable to hemorrhage, injuries take a lot longer to heal and may suffer of spontaneous bleeding (be it a simple nosebleed or severe gastrointestinal bleeding). Chronic hemorrahges cause anemia and iron deficit, and the loss of blood volume lowers the arterial pressure and causes tachycardia. In the worst case, a person can bleed to death with realtively minor injuries.

What type of trait is hemophilia?

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Asked by Wiki User

recessive sex-linked, X chromosome disorders, haemophilia is more likely to occur in males than females.

What is the oldest age you can get hemophilia?

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Asked by Wiki User

No, Hemophilia does not discriminate on age, race or religion.

Hemophilia is a genetic disorder (with the exception of acquired hemophilia) and therefore an individual has hemophilia from the the time they are born until they die.

There is one very rare form of genetic hemophilia where the individual "outgrows" the disorder. In fact, the hormonal changes that take place during puberty increase the production of the clotting proteins to a point above the 50% cut off for being considered as having hemophilia. the genetics however, remain the same.

How does hemophilia affects respiratory system?

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It can cause severe bleeding or hemorrhage which will cause respiratory distress.

What type of doctor treats hemophilia?

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A haematologist does. As blood diseases are not that common, you are not guaranteed to find one in your direct environment. Your general MD will transfer you when needed.

What gender are most people with hemophilia?

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Asked by Wiki User

You would get it from your mother. It is a sex-liked genetic disorder.

Females are the carriers, males exhibit the condition.

What does hemophilia look like?

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Asked by Wiki User

Hemophilia is invisible except when the afflicted person is bleeding, then it is visible in terms of prolonged bleeding, beyond the point when a normal person would have stopped bleeding.

Is Tay-Sachs disease recessive?

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Asked by Wiki User

Yes. In order to develop Tay-Sachs, you must inherit the gene for it from BOTH parents. If you inherit from ONE parent, you can be a carrier, but will not develop the disease. If BOTH parents are carriers, your odds of inheriting Tay-Sachs is 1-4. Other genetic diseases, such as Huntingtons, are carried on a dominant gene- If one parent has gene, odds are 1-2. Link at the bottom of the page for more information on Tay-Sachs:

Is it true that fathers most often pass hemophilia to sons?

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Asked by Wiki User

Partly true, but the girls carry the disease, they usually don"t have it. Hemophilia among women is rare, but does occur. We were so close there was no room, but Only Stacy was immune! ( parody on Melanie song Lay Down) It is obviously about the St. Petersberg massacre.

Can two normal parents produce a hemophiliac son?

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Asked by Wiki User

Approximately 1/3 of the cases of hemophilia are results of random mutations at the time of conception. Thus it is really not that uncommon for two people with completely standard genetics to have a child with hemophilia.

Another possibility is that the mother was a carrier and didn't know. Since Hemophilia is due to a mutation on the X chromosome and females have two X chromosomes, it is possible for her to have no signs or reason to believe that she is a carrier. Even in cases with no family history prior, the spontaneous mutation can effect one of the mother's X chromosomes and then get passed on without her knowing she was a carrier.

Could hemophilia disorder have been prevented?

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Asked by Wiki User

The simple answer is - you can't ! Hemophilia is a genetic medical condition - not a communicable disease. A person is born with the disease. You can't 'catch' it from being in contact with someone - nor is it spread by the person touching surfaces etc. It is treatable - but incurable. A person with Hemophilia has it all their life.

What are some famous cases for hemophilia?

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Abraham Lincoln had hemophilia, along with Mother Theresa and Ghengis Khan, the Owners of Walmart in DesAllemands, and Alexi Romanov, Anastasia's brother

Why is it hemophilia occur mostly in male?

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Asked by Wiki User

"X-linked" disorders are more commonly observed in males do to the chromosomal make up of boys and girls. As you are probably already aware, females have two X chromosomes and no Y chromosomes. Males on the other hand have one Y chromosome and only one X chromosome.

Since this is the case, when a male receives an X chromosome with a mutation on it, they have to use that X chromosome as a "blueprint" even if the information on it is wrong. When a female has a mutation on one of her X chromosomes, she typically has another non-mutated X chromosome from which she can get the correct information.

How common is hemophilia in the US?

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Asked by Wiki User

Hemophilia in the US is considered rare. Affecting mostly males, it occurs in about 13 of every 100,000 people.

I'm not sure where he is getting his data from, however;

I've heard the number 1/10,000 used many times, however there is no single source of data that does not contradict itself.

According to the US Census Bureau the Population of the United States in 2011 was estimated to be 311, 591,917. According to the Centers for Disease Control, there are only an estimated 20,000 males with hemophilia in the United States and considerably fewer females. If we do the math, we see that 311,591,917 / 20,000 says that there is approximately 1 male with hemophilia for every 15,580 people. This means 10 males in approximately 155,800 people.

If we also include the females into these numbers (for which there is very few females, definitely less than 1 female for every 10 males) we would see at most 11 hemophiliacs (both male & female) / 155,800 people which is equivalent to about 7 in 100,000 people.

The strongest source of data really comes from males born with hemophilia each year. According to the CDC, there are approximately 400 male hemophiliacs born each year wich equates to 1/5000 male births. However we must remember the lower than average age of death that lowers this ratio significantly when looking at the population as a whole. In 20 or 30 more years, this will probably become the default ratio as the health care and safety of medications now offer people with hemophilia near normal life expectancies.

What are the symptoms for animals to have hemophilia?

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Asked by Wiki User

Hemophilia has several common symptoms and these include bleeding of the joints and muscles, and prolonged bleeding. Bleeding is not typically faster or different to someone without hemophilia but it takes much longer to stop, typically, and this is the main symptom of the illness.