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Lupus

Lupus (systemic lupus erythematosus) or SLE, is an arthritic autoimmune disease that causes inflammation and pain in various body tissues. The symptoms of SLE can be mild or life-threatening depending on the tissue that is affected. Lupus can affect people of any age and sex, however it is more common in women of childbearing age.

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Can lupus cause lymphnodes to enlarge?

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Asked by Wiki User

Yes. Swollen lymph nodes are a very common symptom of allergies.

When did lupus start?

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Asked by Wiki User

Lupus was first recorded in the 13th century. Chances are, though, it was seen before that. However, since the symptoms of lupus are rather non-specific, it would have been easy to misdiagnose back in those less-medically-advanced times.

What is lupus disease?

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Asked by Wiki User

Nephritis is a condition of the kidneys that is acquired due to having lupus. Lupus is an autoimmune disease in which your immune system goes awry and attacks your own tissues. Your immune system can attack your skin and other organs including your kidneys. When this happens you get lupus nephritis. Approximately 50% - 80% of people with lupus will have their kidneys affected during the disease. There are five classes of lupus nephritis from Class I to Class V with Class IV being the most severe form. The less severe forms of nephritis are often treated with anti-inflammatories such as prednisone and the more severe forms are treated with Cytoxan and Cellcept.

Do patients recover from lupus?

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Asked by Wiki User

The vast majority of people with lupus live a relatively normal life span. People with lupus die of "lupus related complications", the top 3 being organ failure, heart attacks and strokes, and uncontrolled infection. Lupus is not listed as the cause of death, but the complication is.

Is lupus a dangerous?

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Asked by Wiki User

While the majority of cases if lupus are mild to moderate, lupus can also be life threatening. Lupus is an autoimmune disease that can affect any part of the body. If it affects organs, it can be dangerous. The most common causes of death from lupus are kidney failure, uncontrolled infection and cardiovascular events.

How many people in the UK have lupus?

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Asked by Wiki User

Since lupus is not an infectious disease there is no agency to which a diagnosis is reported. The Lupus Foundation of America estimates that 16,000 patients are diagnosed in America each year.

What does an elevated ANA test mean?

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Asked by Wiki User

This is from a web.. i just got a positive ANA test myself, been researching like crazy to figure out what it could be..

http://arthritis.about.com/od/diagnostic/a/ana.htm

Types of Antibodies

In order to understand the ANA (antinuclear antibody) test, it is first important to understand different types of antibodies.

Antibodies are proteins, produced by white blood cells, which normally circulate in the blood to defend against foreign invaders such as bacteria, viruses, and toxins.

Autoantibodies, instead of acting against foreign invaders as normal antibodies do, attack the body's own cells.

http://www.labtestsonline.org/understanding/analytes/ana/test.html#what

ANA shows up on indirect immunofluorescence as fluorescent patterns in cells that are fixed to a slide that is evaluated under a microscope. Different patterns are associated with a variety of autoimmune disorders. Some of the more common patterns include:

  • Homogenous (diffuse) - associated with SLE and mixed connective tissue disease
  • Speckled - associated with SLE, Sjogren's syndrome, scleroderma, polymyositis, rheumatoid arthritis, and mixed connective tissue disease
  • Nucleolar - associated with scleroderma and polymyositis
  • Outline pattern (peripheral) -associated with SLE

Who aqre more likely to develop discoid lupus erythematosus?

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Asked by GaleEncyofMedicine

The tendency to develop DLE seems to run in families. Although men or women of any age can develop DLE, it occurs in women three times more frequently than in men. The typical DLE patient is a woman in her 30s

Does Aloe Arborescens cure cancer when taken internally with honey?

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Asked by Wiki User

No. Cancer occurs when a mutated cell is not destroyed at its creation and then multiplies out of control, simultaneously failing to die off at the appropriate time. This product will not change that. The cancer must be surgically removed and any remaining cells destroyed.

What herbs should people with lupus avoid?

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Asked by Wiki User

People with lupus should always ask their rheumatologists before taking any herbs, vitamins or alternative treatments. Some herbs that "boost" the immune system, like echinacea, make lupus worse. Lupus patients take immunosuppressive drugs to weaken the immune system and stop it from attacking the healthy self. Some of these are very potent chemotherapies and biologics that can interact in dangerous ways with herbs, some vitamins, and alternative therapies.

Is lupus a virus?

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Asked by Wiki User

Lupus is not a virus, it is a malfunction of the immune system.

What causes numbness and tingling in the extremities in MS?

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Asked by Wiki User

Numbness and tingling are one of the early symptoms of MS. Numbness and tingling are a sensory symptom due to the nerves that are responsible for transmitting sensations not functioning properly.

Does Toni Braxton have Lupus?

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Asked by Wiki User

Toni Braxton was diagnosed in 2008 when she was hospitalized with what doctors thought was a heart attack. On further in vestigation, the doctors diagnosed her with lupus. Lupus can affect any of the muscle layers of the heart. Lupus patients are 50 times more likely to suffer a heart attack than the general population.

Lupus located on the body?

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Asked by Wiki User

Lupus can affect any and every part of the body. Most commonly, lupus causes profound fatigue and joint pain. 50% of lupus patients will have kidney involvement. Lupus frequently causes skin rashes and lesions. But lupus can attack any part of the body. Lupus does not spread in the sense of being contagious or like an infection-it is not. Lupus is an autoimmune disease in which the immune system turns against healthy parts of the self.

Is there more than one type of lupus?

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Asked by Wiki User

There are four types of lupus. Cutaneous lupus, often called discoid, is lupus that affects the skin. Systemic lupus erythematosus affects the the body internally, damaging organs and joints. It is possible to have both. Drug induced lupus is caused by certain medications and subsides when the offending medication is withdrawn. Neonatal lupus occurs in newborn babies.

Can weight loss surgery cause lupus?

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Asked by Wiki User

No. In order to develop lupus you have to have the right combination of genes plus triggers. The stress of surgery could trigger lupus in a person who is genetically predisposed, but not in a person who is not genetically predisposed.

What is Lupus anti-coagulant?

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Asked by Wiki User

Lupus anticoagulant is one a several blood clotting disorders that can affect lupus patients. Lupus anticoagulant causes the patient to make blood clots. It is treated with blood thinners.

How does lupus progress?

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Asked by Wiki User

Most cases of lupus fall into the mild to moderate category, although lupus can also be life-threatening. If you have lupus over a long period of time and you have no organ involvement you will probably be OK. If you have lupus and are not monitored for organ invovlement you run the risk of permanent damage. Organ damage in lupus rarely has symptoms until it is quite serious. If you have organ invovlvement and follow your treatment plan and take you immunosuppressive medicaitons you will probably be OK. If you have organ involvement and don't follow your treatment plan you can suffer permanent organ damage and even death.

Lupus patients are at increased risk for heart attack and stroke. The inflammation which occurs as a result of autoimmune activity can affect the blood vessels, resulting in build of of plaques. If these break off they can cause a heart attack or stroke. Long term and repeated use of steriods increases the risk. Lack of regular exercise adds to the problem. For this reason, lupus patients should minimize animal fat in their diets, and eat plenty of fruits, vegetables, whole grains, and plant proteins.

Is lupus anticoagulant hereditary?

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Asked by Wiki User

Researchers have found some genes that are more prevalent in lupus patients, suggesting they may be at least in part responsible for the heritability of the disease. Research however, continues.

What Are Researchers Trying to Learn About Lupus?

Current lupus research projects include:

  • A Specialized Center of Research in Lupus at the University of Virginia School of Medicine
  • A Lupus Registry and Repository that researchers across the country can utilize to help identify genes that determine susceptibility to the disease
  • A Neonatal Lupus Registry that researchers across the country can utilize to research data and genetic information on neonatal lupus
  • Funding for The Lupus Federal Working Group-to focus on lupus research progress
  • Research studies to better understand:
    • Genetics-genes that are associated with susceptibility to lupus or play a role in the development of lupus
    • Biomarkers-something that can be found in cells or tissues that predicts lupus flares or lupus disease process
    • The lupus disease process-how it affects different organs, how it behaves in its earliest clinical manifestations
    • Treatments, such as the medication rituximab, which lowers the number of white blood cells that produce antibodies
    • Overcoming barriers that tend to keep some populations from complying with prescribed treatment.

Science has located genes that are more prevalent in lupus patients, indicating a possibility that they could be responsible at least in part for the disease.
Lupus

is hereditary.
Lupus

is hereditary.

Is nosebleeds a symptom of lupus?

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Asked by Wiki User

Petechia appear as small, pinpoint dots on the skin. They may occur as a symptom of lupus or of other disorders.

What is indicated by Elevated C-Reactive protein and RDW?

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Asked by Wiki User

This seems like a very complex issue. By following the the related link below (Relation Between Red Blood Cell Distribution Width and Inflammatory Biomarkers in a Large Cohort of Unselected Outpatients) more information can be found on this subject.