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Anemia

This category is for questions about the lack of red blood cells or hemoglobin called anemia: its symptoms, causes, and treatment.

936 Questions

What are the dangers of alcohol abuse and sickle cell trait?

People who have sickle cell should try to avoid consuming alcohol if at all possible. This is because sickle cell causes the patient to become dehydrated in the first place, so drinking alcohol would only exacerbate the problem.

What is the difference between haemophilia and anemia?

Hemophiliacs have normal platelet counts, they bleed because their clotting factors (proteins made by the livers created to help our blood clot when we are bleeding) level is less than 1% vs normal non bleeders @ 50%-100% Hemophiliacs are missing either Factor VIII or Factor IX in their blood (for Hemophilia A or B, respectively). It is due to a defective gene located on the X chromosome. The defect causes the liver (where clotting factors are made) to not produce the needed clotting factors etc

A person with abnormally low platelets is completely different situation/condition called thrombocytopenia and has different signs and symptoms from clotting factor problems like hemophilia.

Now, in contrast, anemia is having too few red blood cells (the cells that make blood red and carry oxygen to all of the cells and tissues in the body) circulating in the bloodstream. It is possible to have both anemia and a hemophilia, to have one without the other, or to have neither one.

What component of blood is impacted by sickle cell anemia?

Red Blood Cells. It is called

sickle cell because some of the red blood cells

are long and shaped like sickles. Although sickle

cell disease primarily affects African Americans,

it is also found in Hispanics, Italians, Greeks and

people of Mediterranean descent.

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Can a 3 year old be anemic?

A three year old child needs 11.1-13 grams of Hemoglobin per deciliter.

http://kellymom.com/nutrition/vitamins/iron/
http://www.irondisorders.org/children

Is it safe for someone with sickle cell to have a baby?

Answer

As you already must know Sickle Cell disease is genetic, but the GOOD NEWS is there is no known risk that babies may develop sickle cell disease.

It's a good idea to first check with a genetic specialist and make your decision from there.

Good luck!


Lack of intrinsic factor?

Definition

Intrinsic factor is a natural substance normally found in the stomach. You need this substance to absorb vitamin B12 from foods.

A lack of intrinsic factor leads to pernicious anemia and vitamin B12 deficiency, which can cause anemia and brain and nervous system (neurological) problems.

Alternative Names

Intrinsic factor - lack of

Causes, incidence, and risk factors

Babies that are born without intrinsic factor cannot properly absorb vitamin B12 starting around age 6 months. Children who have the juvenile type of lack of intrinsic factor tend to show signs and symptoms after age 10.

Older adults get pernicious anemia, which is caused by a lack of intrinsic factor production. This is usually due to an autoimmune disease that causes the stomach lining to waste away (atrophy). The stomach lining is where intrinsic factor is usually made.

References

Antony AC. Megaloblastic anemias. In: Hoffman R, Benz EJ, Shattil SS, et al., eds. Hematology: Basic Principles and Practice. 5th ed. Philadelphia, Pa: Churchill Livingstone; 2008:chap 39.

What is the recommended treatment for pernicious anemia?

Pernicious anemia can be treated with injections of vitamin B12, and possibly with B12 vitamin pills. Pernicious anemia is a vitamin B12 deficiency disease, B12 is required to make healthy red blood cells and can normally be obtained from animal based foods, including, meats, fish, dairy products and eggs (but not plant foods), however, when people choose not to eat animal products, vegans for instance, they may suffer a B12 deficiency. Also, inadequate absorption can occur when there is an insufficient amount of a specific protein referred to as "intrinsic factor" in the body that is normally released by stomach cells.

Why there is dyspnoea in anemia?

Dyspnea is the medical term for shortness of breath. It can be a present symptom when one is having anemia because of the oxygen binding nature of our blood cells and being anemic means your blood cells have a deficiency.

Will a tattoo affect sickle cell disease?

No, tattoos will not effect the disease. Just be sure to take your regular antibiotics if needed to prevent any infections.

What tipe of food is good to eat if you have anemia?

lots and lots of iron :)

lots and lots of iron :)

lots and lots of iron :)

How does anemia affect your circulatory system?

Aneamia doesn't afffect your ciculatory system per se. It affects all the cells that make up your body and organs. They do not get enough oxygen to function.

What is the common name for sickle cell anemia?

It is a genetic disorder.

However...

It is also a protection against malaria.

For example, if a person were born in an area where malaria is present, he or she would likely die from the disease, unless he or she inherited 1 sickle cell gene.

Malaria viruses reproduce in the red blood cells. The parent virus invades a cell, and uses the cell as a host to grow more viruses.

With 1 sickle cell gene, malaria viruses that invade a red cell are quickly destroyed, since the red cell collapses, preventing the virus from reproducing.

But with 2 sickle cell genes, red cells collapse too easily; just a bruise can cause someone to become anemic when too many red cells collapse.

In the real world, people with no sickle cell genes died from malaria. People with 1 sickle cell gene survived. People with 2 sickle cell genes died from sickle cell anemia.

It was natures way of assuring that at least half of the population survive, but it is certainly a difficult thing to live with today, now that we can more easily treat malaria.

List of 10 noncommunicable diseases?

A noncommunicable disease is one that cannot be spread. They are not contagious. Most noncommunicable diseases are caused by hereditary factors, lifestyle choices, or just genetic abnormalities. Some of the top noncommunicable diseases are:

  1. Arthritis: Inflammation of the joints in the body, there are many types
  2. Asthma: Inflammation in the airways, difficulties breathing
  3. Cancer: Abnormal cell growth in the body, there are many types of cancer that effect both men and women of all ages
  4. Hypertension: High blood pressure
  5. Diabetes: High sugar (glucose) levels
  6. Depression: Feeling sad, hopeless, worthless, loss of energy, death or suicide thoughts, maybe even some weight changes
  7. Alzheimer's: Affects older adults, memory loss occurs
  8. Osteoporosis: low bones mass, weakness
  9. Heart disease: Includes angina, heart attack, congenital heart disease, heart failure, etc.
  10. Fibromyalgia: Problems with soft tissue in the body, pain in the tissues of the body

Is sickle cell disease more common in boys or girls?

The incidence of sickle cell disease is equal in both men and women.

However, it is believed that men who have the disease experience worse symptoms than women with the disease.

A possible reason for this is the role of oestrogen in the female body. Oestrogen helps stimulate the production of nitric oxide. Scientists believe that nitric oxide has a key role to play in reducing the symptoms of a sickle cell crisis as it dilates blood vessels, giving the sickle shaped cells more room to pass through the vessels, preventing blockages which is the cause of sickle cell crisis.

A deficiency of vitamin b12 leads to which type of anemia?

Megaloblastic (Macrocytic) Anemia. Basically the Red Blood Cells have a larger volume (MCV).

How do you cure aplastic anemia without bone marrow transplant?

medical therapy of aplastic anemia often includes short course of anti thymocyte globulin (ATG) or anti lymphocye globulin and several months of treatment with ciclosporin to modulate the immune system.mild chemotherapy with agents such as cyclophophamide and vincristine may also be effective.steroids are generally ineffective though are often used to combat serum sickness caused by ATG

Is Beta Thalassemia fatal?

People whose hemoglobin does not produce enough beta protein have beta thalassemia. It is found in people of Mediterranean descent, such as Italians and Greeks, and is also found in the Arabian Peninsula, Iran, Africa, Southeast Asia and southern China.

There are three types of beta thalassemia that also range from mild to severe in their effect on the body.

Thalassemia Minor or Thalassemia Trait. In this condition, the lack of beta protein is not great enough to cause problems in the normal functioning of the hemoglobin. A person with this condition simply carries the genetic trait for thalassemia and will usually experience no health problems other than a possible mild anemia. As in mild alpha thalassemia, physicians often mistake the small red blood cells of the person with beta thalassemia minor as a sign of iron-deficiency anemia and incorrectly prescribe iron supplements.

Thalassemia Intermedia. In this condition the lack of beta protein in the hemoglobin is great enough to cause a moderately severe anemia and significant health problems, including bone deformities and enlargement of the spleen. However, there is a wide range in the clinical severity of this condition, and the borderline between thalassemia intermedia and the most severe form, thalassemia major, can be confusing. The deciding factor seems to be the amount of blood transfusions required by the patient. The more dependent the patient is on blood transfusions, the more likely he or she is to be classified as thalassemia major. Generally speaking, patients with thalassemia intermedia need blood transfusions to improve their quality of life, but not in order to survive.

Thalassemia Major or Cooley's Anemia. This is the most severe form of beta thalassemia in which the complete lack of beta protein in the hemoglobin causes a life-threatening anemia that requires regular blood transfusions and extensive ongoing medical care. These extensive, lifelong blood transfusions lead to iron-overload which must be treated with chelation therapy to prevent early death from organ failure.

From Jagadish