Multiple Sclerosis

One of the conundrums surrounding MS is that it has no symptoms which are unique to it. Every symptom you can experience in MS can be attributed to something else. A diagnosis of MS, therefore, is a diagnosis of exclusion. When you exclude everything else which could be causing that symptom, it can only be MS.

MS also cannot be conclusively diagnosed using any imaging or chemical analysis. These things point to MS, but they are not conclusive.

Part of the diagnosis of MS is the experience of the relapses themselves. In order to be diagnosed with clinical MS, you need to experience two distinct episodes disseminated by space and time. Dissemination of space means two separate physical systems, while dissemination of time usually means about six months.

About the best you can hope for is a single, clinically isolated event, and no further relapses. While it can't officially be diagnosed as clinical MS, it can be treated that way. Studies are attempting to show whether or not early intervention (after the initial event) with disease-modifying medication can prevent full-blown clinical MS.

To answer your question, you need to experience at least one relapse before you can officially be diagnosed with possible or probable MS.

Thank you for your reply, this information is really important to me!! But your answer also raised further questions! (And since I've tried researching this online and elsewhere and got lost in the heap of info, I'll go ahead and ask some more). My mate had a single episode which led him to the hospital and after a spinal tap, MRIs and all those great tests, he was diagnosed with MS. He has ever since been treated with disease-modifying drugs (which he hates as they are injected) and never had another episode since. That is he hasn't had any other episode since the first one in 4 years except for a strange sensation in his spinal chord which he and other MSers describe as "electricity running up your spine" which occurs rarely.

My question is: Is it possible that he may never have another episode? (If such a thing can be predicted!!) And since there is absence of episodes for such a long time is it worth continuing the treatment? I am asking this because all those injections and blood tests and MRIs can take a significant toll on the psychology of someone afraid of needles.

I would be very grateful for another reply as I haven't had the chance to speak with a doctor about this yet.

---------------------

Fear not, there is hope!

Specifically, there are a few things that may help to put your mind at ease slightly.

1. While it is not possible to predict whether or not you will have another relapse, what is known from empirical studies is that the longer you go without a relapse, the longer it will likely be before you have another. For example, if it's been five years since your last relapse, all else being equal, it will possibly be another ten years before you have another.

2. For the needle-phobic, there is a new therapy that is just making its way on to the market, and it is oral (i.e. it's a pill). There is expected to be at least one of the pills approved this year. If using needles is interfering with you getting treatment, this may be an option that you and your neurologist can discuss.

-------------------

Again I am grateful for the reply!

I know about the pill but my mate's doctor said "you don't change from a treatment that seems to be working fine to the pill just because you don't like the needle".... I guess he's right but we'll see into that again when it gets approved.

The way I understand it though is that nobody can completely exclude a future relapse no matter how long you go with no episodes.

Not that I complain, things are as good as they could be! A big thanx to all who took the time to reply and helped me understand some things better!

Wikipedia mentions that Multiple Sclerosis, which is an inflammatory disease, is highly susceptible to occur in individuals with low levels of uric acid, as mentioned as follows: "Gout occurs less than would statistically be expected in people with MS, and low levels of uric acid have been found in MS patients as compared to normal individuals. This led to the theory that uric acid protects against MS, although its exact importance remains unknown".

A profusion of uric acid in the human body is prone to induce kidney stones which high levels of kidney stones have been correlated to large consumption rates of Vitamin C. So far, we can determine a clear correlation between MS and a reduction of vitamin C in the diet.

Also, because Vitamin C (which is an antioxidant that is known to prevent the formation of oxidative stress) helps to reduce inflammation and prevent the occurrence of infectious diseases, I'm assured that a regular consumption of Vitamin C can inhibit or reduce the production of inflammation of the nervous system, which in turn can prevent MS.

To answer your question abruptly: Yes, a lack of Vitamin C will most likely produce Multiple Sclerosis in individuals that are deficient of Vitamin C.

Just a warning from my research: Both a deficiency or an overuse of Vitamin C can cause inflammation. So to be careful, consume Vitamin C in large quantities that is respectively healthy for a normal functioning person, but be sure to not overdose, even though it's highly rare to overdose on Vitamin C. Just be cautious.

MS normally begins when younger, at an average age of 35 and almost always before 50, while Parkinson's Disease begins in the late years at an average age of 65 and the likelihood increases as one gets older.

MS is an autoimmune disease where the immune system attacks the covering of the nerves causing nerves not to transmit and receive signals to/from the muscles required for them to function. Parkinson's originates in the brain caused by the loss of dopamine neurons. This causes signals to fail between different parts of the brain that control movement.

yes

In some cases, MS is highly hereditary; but not always. The sad fact is, very little is known about MS except for what will eventually happen to someone who has it (increasing disability and eventual death). Inheriting the illness is uncommon enough that some doctors still try to say it is not hereditary as if it were a proven fact. There is most definitely some genetic factor in some cases of MS, however. Henry (Gizmo) Williams, a famous athlete who used to play for the Edmonton Eskimos in the CFL has lost more than 20 members of his family to MS. I am the first and so far only member of my family to be afflicted; so in my case there is no genetic influence. Instead of trying to find the cause of MS and prevent or treat it, researchers just concentrate on trying to find new drugs to slow the progression of the illness; which has been proving to be for the most part a futile endeavour.

3 6 9 12 15 18 21 24 27 30 33 36 39 42 45 48 51 54 57 60 63 66 69 72

Babinski's sign is caused by a lesion in the corticospinal tract (UMN) that produces a characteristic pathological sign of extension of the great toe and fanning of the remaining toes. This also occurs in infants before the corticospinal tract is fully developed, in adults during sleep, or sometimes in adults after strenuous walking or running.

no

Amytropic Lateral Sclerosis is noncommunicable.

MRI

my brother has the syndrome it means that the person has to wear splints (a plastic type of thing that goes in your shoe) it caus's the persons feet to turn out making them not able to lift their foot up high. it can causes nerve dammage to the feet .

im not sure it is that :S :L i have it at the moment.. it was first found in America when people where having Swine Flu jabs for some reason.

the syndrome attacks the nervous system working its way up. it first starts in the hands and feet and then stos youre legs from working it can reach youre face as i have expereinced although its extremelly rare that it kills you. when it reahces youre face it givesa up attacking you and works its way back down you can be ill with it for up to 2 months you get given steriods and so on hope this helped!

20000 x 8080 = 161600000

Multiple sclerosis causes the myelin sheaths around the axons in the neurones to be destroyed. The myelin is an insulator and so if it is not present, ions will flow across the nuerone membrane, thus slowing or even inhibiting action potential(nerve impulses)

No it effects myeline sheath

If you're more than 15 years old, the answer is no, there really is no way to prevent MS that we know of today. Vitamin D has been shown to have preventative effects, but what quantity and at what age are as of yet unknown, and Vitamin D can be dangerous at high levels, so I don't advocate taking excessive Vitamin D.

There are a lot of factors that go into determining your susceptibility to MS, including where you live, your ethnicity, your sex, your family history of MS, and finally exposure to some infectious trigger while you're younger. Even these are still poorly understood.

Suffice it to say that the average person in society has about a 1 in 750 chance of developing MS.

One is a factor of every number. One is only a multiple of itself.

Of particular concern is the finding that people with multiple sclerosis have increased levels of the enzyme glutaminase (the enzyme that converts glutamine into glutamate) in areas of nerve fiber damage. High levels of glutamine in the diet would increase glutamate levels near these injured areas magnifying the damage. It has been shown that excitotoxicity plays a major role in multiple sclerosis by destroying the cells (oligodendrocytes) that produce myelin. Russell L. Blaylock, M.D.

0,02637 seconds -> Fast.

Understand that this information is very, very preliminary, and researchers don't understand the mechanism by which this works.

Researchers noted that the incidence of neurological impairment in elderly Indian populations was very slight, and started investigating their diets to find links to prevention of MS. Curcumin was also recently identified as a potent anti-inflammatory agent, effective in wound healing. And just last fall, researchers at UCLA reported that curcumin appeared to slow the progression of Alzheimer's in mice.

A recent study has found that giving injections of 50- and 100-microgram doses of curcumin (a curry compound) to a group of mice bred to develop a disease called experimental autoimmune encephalomyelitis (EAE) slowed down their progression of the disease. EAE is similar to MS and is used as a model for MS research.

Researchers administered the doses three times a week over a 30-day trial. By day 15, mice who had not received curcumin developed EAE to such an extent that they displayed complete paralysis of both hind limbs. Mice given the 50-microgram dose showed only minor symptoms, such as a temporarily stiff tail. And mice given the 100-microgram dose appeared completely unimpaired throughout the 30 days of the study.

LDN can help multiple sclerosis. It can also treat numerous other disorders. It was first used on people with AIDS. A recent study showed improvement in people's health when using LDN.

M m is an m, an upside down w, and/or a delicious candy. Mini's are always the best don't argue

yes