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Down Syndrome
What a difference an extra chromosome can make. Here we explore the misconceptions -- as well as the ups and downs -- of Down Syndrome, a congenital genetic disorder that is caused by the presence of an extra 21st chromosome. The affected person is mildly to moderately handicapped, short in stature, and has a flattened facial profile.
693 Questions
Fragile X Syndrome
How is premenstrual syndrome diagnosed?
No tests, depends on physical and mood symptoms. Symptoms occur 5-11 days before the period begins, cease when the period starts, occurs for at least 3 consecutive menstrual cycles.
no, it is caused by a triplication of the 21st chromosome. its not contagious in any way.
If you have some sort of mental retardation does that mean you have Down syndrome?
No. Down's is only one of millions of reasons to become retarded. While it used to be thought that only children with Down's were the only ones who were mentally retarded, it is now known that Down syndrome is only one of the hundreds of known causes of a child being mentally retarded.
It's even been documented that one-third of the children who are mentally retarded have no known cause.
Two other major known causes are Fragile X and Fetal Alcohol Syndrome Disorder. Like Down syndrome, Fragile X Syndrome is a chromosome abnormality.
However, FASD is not a chromosome abnormality. FASD is the only preventable -- 100% preventable -- cause of mental retardation. It is also the only one that is 100% untreatable. It's actually been estimated that FASD affects 40,000 infants each year. That is more than Spina Bifida, Down syndrome and Muscular Dystrophy combined.
Lots of research is being done endlessly -- with parental education being the most important.
How were people with Down syndrome treated back in the day?
It depends where in the world they were. It ranges from living a dejected/shunned life to complete cure. Some places it was not tolerated, in others cured.
There are certain ancient practices which allow for easy treatment. It is said that most of the autistic cases are past life trauma. People knowledged and proper practitioners were able to assist those in need during the earlier days.
That true knowledge is mostly lost and fewer know it today. Hence modern medicine.
The reasons for autism consist a wide area. It can be for myriad reasons. Trauma is a prominent one. Dejection is another.
Treating autism in childhood is the best option. As the individual grows, patterns:- mental and physical get set and become harder to resolve. At that stage more serious medication will be needed. During childhood however, many a time it can be accomplished using no such or bare minimal medication.
In the earlier days people only had what was on hand. This day of information was not available to them. So they paid more attention to their surroundings and did what they could, if they could gather a solution they did. If they could not they let live.
Also, in earlier years experienced autism was one-forth of what it is today.
Can Down syndrome spread to other people?
No, Down syndrome is not contagious. It is a genetic/chromosomal difference - some may equate it to a birth defect, others to a birth enhancement
Does Hannah Gosselin have down syndrome?
No she does not. The prominence in the foreheads of most of the children is caused by the inherited Asian genes from the father.
What causes down syndrome to spread?
It is a genetic disorder caused by the presence of all or part of a third copy of chromosome 21. It is typically associated with physical growth delays, characteristic facial features, and mild to moderate intellectual disability.
What celebrities have relatives with down syndrome?
Famous people with Down syndrome include:
- Stephane Ginnsz, actor - In 1996 was the first actor with Down syndrome to play the lead role in a movie (Duo).
- Pascal Duquenne, Belgian film actor, co-starred with Daniel Auteil in the 1996 film Le Huitième Jour (The Eighth Day). Both these actors won a joint award for Best Actor at the Cannes Film Festival.
- Joey Moss, Edmonton Oilers locker room attendant.
- Isabella Pujols, adopted daughter of St. Louis Cardinals first baseman Albert Pujols and inspiration for the Pujols Family Foundation.
- Paula Sage, Scottish film actress and Special Olympics netball athlete. Her role in the 2003 film AfterLife brought her a BAFTA Scotland award for best first time performance and Best Actress in the Bratislava International Film Festival, 2004.
- Chris Burke, American actor who portrayed "Corky Thatcher" on the television series Life Goes On and "Taylor" on Touched by an Angel.
- Edward Barbanell, played Billy in 2005's The Ringer.
- Danny Alsabbagh, Australian actor who played Toby in the Australian mockumentary series Summer Heights High.
- Tommy Jessop, British actor who played the role of Ben in Coming Down the Mountain, opposite Nicholas Hoult.
- Rene Moreno, subject of "Up Syndrome" - a documentary film about life with Down syndrome.
- Nigel Hunt, British author of "The World of Nigel Hunt; The Diary of a Mongoloid Youth." This book was published in 1967, when "mongoloid" was still quite commonly used to refer to people with Down syndrome.
- Hilly, Sam, Lucy and Megan, 4 friends with Down syndrome who share a house in Brighton with their friend Lewis, who has Williams Syndrome. Their lives are followed in the Internet documentary series The Specials.
- Pablo Pineda, Spanish actor who starred in the semi-autobiographical film Yo También.
- Jason Kingsley - actor
- Eric Ruthven - MBE
- Miquel Tomasin - singer
- Karen Gaffney - swimmer
- Judith Scott - artist
What week of development does down syndrome occur?
At age 30, for example, a woman has about a 1 in 900 chance of conceiving a child with Down Syndrome. Those odds increase to about 1 in 350 by age 35. By 40 the risk rises to about 1 in 100.
It occurs by going through fermentation and supplies alcohol in the brain resulting in down syndrome.
Is high risk of Down syndrome mean that the baby has it?
No. Both the scan and the blood test just give a higher or lower risk of Down's syndrome based on your age. For a diagnosis you will have to have an amniocentesis. You need to talk with your doctor, a counsellor and your partner to work out your next step.
What is the possible outcome of Down syndrome?
The likelihood of an individual with down syndrome to conceive a child is extremely rare. There is infertility among both males and females with Down syndrome; males are usually unable to father children, while females demonstrate significantly lower rates of conception relative to unaffected individuals. Women with DS are less fertile and often have difficulties with miscarriage, premature birth and difficult labor. Without implantation genetic diagnosis. approximately half of the offspring of someone with Down syndrome also have the syndrome themselves. Men with DS are almost uniformly infertile,, exhibiting defects in spermatogenesis. There have been only three recorded instances of males with Down syndrome fathering children
Can a history of chlamydia cause your baby to have Down syndrome?
You can miss-carry from a STD, depending on which one it is.
More than likely no; but it is possible.
Yes STDs can cause miscarriage.
Yes as an epidemiologist it is my job to watch STIs. I know that many of the STIs out there if they don't get cured can cause serious damage to a unborn infant but you can get treated to have the child resist the effects of the STI so they can be born normally or to avoid it they can do a Ceserian Section if necessary
What are two major causes responsible for Down syndrome?
Down syndrome is the most common genetic cause of ID (intellectual disability). Down syndrome is caused by trisomy for chromosome specifically, duplication of 21q22.
- 95% of cases result from nondisjunction and resultant standard trisomy 21.
- The remaining 5% are relatively evenly split between robertsonian translocation, of which 14;21 translocation is most common and about half are familial.
note :
robertsonian translocation is a common form of chromosomal rearrangement that in humans occurs in the five acrocentric chromosome pairs, namely 13, 14, 15, 21, and 22.
How does down syndrome affect you intellectual?
Down syndrome is the most common genetic cause of learning disabilities in children. People with Down syndrome often have trouble remembering things they have learned and have no motivation to remember things that has no physical meaning to them. Down syndrome causes mild to severe mental retardation. Mental retardation is recognized as impaired learning, social, and vocational ability. This means that cognitive development is stunted. Children with Down syndrome often have to learn in special Ed classes, as normal classes may not be meeting the child's learning needs. Although individuals with Down syndrome can graduate high school, most will only have the IQ of an 8 year old. Another common problem with cognitive development for children with Down syndrome is the ability to generalize - to apply what they have learned in one a situation to another situation. Children with Down syndrome often have to be taught one thing multiply times. Short attention spans have been noted in children with Down syndrome.
What is the average life span for people with trisomy 21?
People with Down syndrome probably live for 60 years. Because the genetic materials in chromosome 21 are the smallest numbers so the effects are serious but not lethal. Even thought when one is missing, that person would live for a long time in his life
How can down syndrome affect a child physically emotionally socially and intellectually?
Down's syndrome will give your child a total amount of 47 chromosomes in his/her somatic cells as opposed to the normal human who has only 46 chromosomes in his/her somatic cells. In addition Down's syndrome will lower the metal ability of the child and will give the child distinct facial features (such as a very circular face).
It also affects the fertility of the child as well. Males are mostly sterile and females can be fertile, but it is very hard to have a baby. Usually the baby is prematurely born, aborted naturally, or needed surgery to take out.
What race does Down syndrome affect?
Down Syndrome affects all races.
Down Syndrome does not affect all races evenly its affects Mexicans more than any one else.
Hispanics have larger numbers of live births suffering from Down Syndrome because they do not terminate their DS pregnancies, like other races do.
Is down syndrome autosomal or sex-linked?
No. It is due to a non-disjunction problem when the sperm and egg meet to form a zygote.
Is there any link between Aspergers and Down syndrome?
I have refractory ceoliac type 2 which means I have non hodgkins lymphoma. I also suffer from Aspergers (diagnosed). I would be surprised not to find a link between undiagnosed ceoliac disease, Autism and cancer. A lot of Autistics have issues with the proteins in gluten/wheat and dairy due to a leaky gut causing toxicity. Chronic inflammation and Candida are also a common problems in which cancer can cohabitate. Not all will end up with cancer but it is certainly possible.
