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Laboratory Testing

Before a doctor can diagnose a patient, laboratory tests such as blood work are required.

8,512 Questions

If Vitamin D is very low and urine calcium very high 750 and so is pth what does this mean?

In most cases, high calcium, high PTH, and low vitamin D point to Parathyroid Disease. This is normally caused by a benign parathyroid tumour, which will not go away on its own and must be removed.

PTH stands for Parathyroid Hormone. The normally rice-sized parathyroid glands are not actually related to the thyroid itself (they just live next to it), and are responsible for regulating your calcium levels. This is all that they do. The four parathyroid glands act as a sort of thermostat system, controlling the amounts of calcium in the body. The parathyroids are very sensitive to calcium levels, "turning on" (releasing PTH) when they detect your calcium going low, and "turning off" (not releasing PTH) when they detect your calcium going high. They're normally quite precise in detecting and reacting to calcium.

Calcium is crucial for your electrical systems - nervous system, brain, muscle impulses, etc. - to function normally. Because calcium is so critical, a primary function of your bones is to maintain calcium reserves, acting as a sort of calcium "bank" from which you can withdraw calcium whenever you need it. When your parathyroids detect your calcium going low, the release of PTH tells your bones to release their calcium, and when your calcium starts to increase, the parathyroids stop PTH, telling your bones to start storing calcium. This back and forth should normally happen many times per day, keeping the calcium available to your brain, muscles, heart, and nervous system inside a very precise range.

A parathyroid tumour causes one (or in rare cases, more) of the four parathyroid glands to overproduce PTH, essentially becoming stuck in the "on" position. Your bones get a constant signal to release calcium, which causes a lot of problems:

  • Your bones essentially break down, as they constantly dissolve far too much of their calcium into your blood stream. This causes osteoporosis - even in young people.
  • Since vitamin D is what your body uses to help absorb more calcium from your diet, your body detects all of this extra calcium and puts the brakes on the vitamin D to protect itself from absorbing even more of it. This vitamin D deficiency brings a bunch of its own problems.
  • The overload of calcium can become too much for your electrical systems, which can start to go out of whack, causing depression, memory loss, and other brain symptoms, heart symptoms, and musle cramps, among other things. Excess calcium is very hard on your body.
  • Your kidneys will have a hard time dealing with all of this extra calcium, which can cause kidney stones or other kinds of kidney damage over time.
  • Excess PTH and calcium is particularly bad for a pregnant woman. The baby's parathyroid glands, detecting high calcium, can fail to activate or even fail to develop at all - which can bring an extremely elevated risk of miscarriage or life-threatening problems if there is a live birth.

High calcium is NEVER normal, and it should NOT be watched to "see if it goes down." It will not. If your doctor tells you this, immediately find a new doctor.

If you have a parathyroid tumour (which is almost always benign - NOT cancer), it must be removed or your symptoms and the damage it is doing to your body will only get worse.

You can find much more information at www.parathyroid.com

How long does cannabis tincture stay in your system?

It has been tested time and time again from sceintists such as the federal investigation for drug abuse, and according John Smith "We have tested it numurous times, and according to each one, not one single test was positive for the cannabanoid THC." Further more, tinctures or as some may call it "marijuana tinctures" do not show up, on a drug test.

Where is lh made?

Leutnizing hormone is produced in the anterior pituitary gland

What type of fasting is required before a urine test?

Patients do not have to fast or change their food intake before a urine test. They should, however, avoid intense athletic training or heavy physical work before the test because it may result in small amounts of blood in the urine.

What is T4 free blood test?

Thyroxine free index. "elevated TsH and low fT4 or fTi indicates primary hypothyroidism due to disease in the thyroid gland. a low TsH and low fT4 or fTi indicates hypothyroidism due to a problem involving the pituitary gland. a low TsH with anelevated fT4 or fTi is found in individuals who have hyperthyroidism."

What are DNA microarray tests?

I am afraid is quite an in-depth subject.

in layman's terms, if you imagine a glass slide with lots of very small dots (500,000 of them). these dots (probes) are complementary DNA, which has been stuck to the slide.

If you then take a sample of mRNA (expressed DNA) from the patient and turn it into DNA (cDNA). If you then put that cDNA on top of the dots on the slide and incubate, if that patients gene is being expressed it will bind to the probes stuck on the glass. This binding to the probe causes fluorescence, which can be detected.

If you compare the expression patterns between a healthly individual and a diseased individual you can try and work out what genes are being expressed differently in that condition (for research purposes). If you already know a certain gene is over expressed in a disease (e.g. BRAC2 in breast cancer), you can then diagnose the patient.

Likewise you can use microarrays to predict what diseases you may develop in the future - for example you may be found to have a gene found in Alzheimer's for instance.

This is a very very brief introduction to the subject and its very interesting, you may like to try the following link if you'd like some more information on the subject.

http://plasticdog.cheme.columbia.edu/undergraduate_research/projects/sahil_mehta_project/work.htm

What does a GFR of 82 mean?

A GFR or the glomerular filtration rate that is 82 means that someone has 2nd stage disease in the kidney. The function of the kidney that is normal declines through age.

In a blood group determination experiment after the finger is pricked the first drop of blood is usually wiped off Why?

Possible contamination of the sample by the instrument (lancet) used to obtain the droplet. The second drop of blood would be the better sample.

In a urine sample what does mixed growth mean?

If a urine sample has mixed growth then it means that there are more than one type of bacteria growing in it.

What is ALT in a comprehensive metabolic panel?

ALT is part of the liver function tests alanine aminotransferase. AST - aspartate aminotransferase. ALT/AST ratio is used to help diagnose liver disease and injury.. Likely from alcohol, drugs, or viruses such as a Hepatitis viral infection.

Coffee with milk and sugar before blood tests?

a few lab investigations require empty stomach.

for fasting sample it is not good to take coffee before blood tests.

Should you take blood pressure drug before fasting blood test?

Fasting labs are not affected by blood pressure medications and they should be taken as prescribed. Simply take them with some water of plain black coffee on your regular schedule.

Can you pass a drug test with sure gel 2 days before test?

chances are, no, it will just clog your system up.. and most modern drug tests have other factors to think about.. they can usually see if your system is 'diluted' in other words. even drinking too much water can fail you.. i hate to tell you this, but your best bet is just to quit doing them.. best of luck

Is there anyway to beat an alcohol urine test?

dont drink alcohol for 24 hours

or

drink as many nonalcoholic beverages as you can

to detox the liver

Will a gel containing 67.0 percent ethyl alcohol be detected during ETG test?

It could happen. We can't say for sure. We wouldn't chance it. Wash your hands instead.

What is the medicinal use of nitric acid?

Nitric acid in clinical therapeutics in homeopathy is used to treat mental symptoms of sadness,anxiousness,cephalalagia and skin diseases.