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Muscular Dystrophy

Muscular dystrophy is a group of genetic diseases that cause rapid muscle degeneration. Duchenne muscular dystrophy is the most common form. All questions relating to muscular dystrophy can be found here.

500 Questions

What are symptoms or effects of muscular dystrophy?

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Asked by Wiki User

In the mild form, persons usually develop cataracts and experience mild muscle tone dysfunction (myotonia). They normally do not experience clinical manifestations until they reach 20 years of age

How many different types of muscular dystrophy are there?

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Asked by Wiki User

Three main types

  • Spastic (most common)
  • Dyskinetic
  • Ataxic (least common)

CP can also be a combination of more than one type, each have there own unique characteristics. CP can also affect a different number of limbs - it can be quadriplegic (all four limbs affected), triplegic (three limbs affected), diplegic (two limbs affected), monoplegic (one limb affected), or hemiplegic (one side of the body)

What famous people have Muscular Dystrophy?

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Asked by Wiki User

Dr. Hue G. Rection had it. he was the one that found out about the nucluse in a cell and he had a HUGE dick

How much money does jerry Lewis get from muscular dystrophy?

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Asked by Wiki User

None. However, he skimmed 75%+ from ALL donations so he could pay his "BUDDIES". The lazy Jew figured it all out. So did everybody else eventually. That is why the big stars never came on his show and the ones who did only came once. They were duped into appearing for free (oops, they go a free lunch and a drink) while feeling their need to help.

Adios you free loading fraud.

How is DMD treated?

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Asked by Wiki User

soo all u do is go to the doctor and ask for a taco(:

Is duchenne muscular dystrophy hereditary?

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Asked by Wiki User

yes it can be only if you are 18 or older

Does muscular dystrophy hurt?

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Asked by Wiki User

Basically in younger ages you don't feel much pain, but as the M.D. progresses basically you lose your balance and fall alot. I walked on my tiptoes because my tendons were too tight which is like having cramps in your muscles all the time. By the time I was in a wheelchair, the pain and cramping had stopped. I was 7 then...By 9 I was in an electric chair because the tendons and muscles shrunk i have all the sensation in my body like you, but i cant scratch my own nose. That's pain... lol. That being said, the older I get the more pain there is. My bones are squishy and are easy to break which I have done a few times.Back gets sore due to the curvature of my spine ...gravity sucks. You also sit all day which gives me a numb butt and hurts my tailbone. The worst thing for me is the fact that the diaphragm muscles got to the point I needed physio every time I got a cold so I could cough up the crap in my lungs. Cracked a few ribs here wasn't fun. I got so sick that needed medical intervention. I ended up on a trache and ventilator that breathes for me (m.d. means muscles don't work... try to flick that spider off your hand...cant move, that's also painful) Getting suctions to remove the excess secretions in my lungs that builds up because i cant cough means that my lungs get a rubber hose shoved in them all the time and it scratches and cuts the lining of your lungs so it bleeds and burns which can also lead to illness. The final for me would be the microtears I get in my muscles every two to three weeks. Its like spraining your ankle all the time same kind of pain. It is not unmanageable, I use medical cannabis. It helps stop cramping and relieves tension and tightness in muscles as well as numbing the microtears and muscle aches. I am 31 and hope I have answered your question.

Dale

Why is breathing affected by muscular dystrophy?

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Asked by Wiki User

First of all, it matters what type of MD you have, but generally since the disease weakens your muscles to the diaphragm, intercostal muscles and other muscles involved in breathing begin to die, and make breathing harder and harder.

What is dystrophinopathy?

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Asked by Fabfour

a dystrophinopathy, is normally associated with both Duchenne and Becker muscular dystrophies. Dystrophinopathy literally means "abnormal development disease" generally related to muscular development in pediatrics.

How many people in America have dmd?

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Asked by Wiki User

2,000,000 people globally

How can two unaffected people have a child who has Duchenne muscular dystrophy?

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Asked by Wiki User

This is exactly how DMD is transmitted: the defect resides on the X chromosome. Women have 2 X chromosomes, so even if one of the X chromosomes has the DMD trait, the other X chromsome does not and they never get DMD.

This is why boys exclusively get Duchenne - they have only one X chromosome.

So if a woman carries the Duchenne trait, there is a 50% chance that she will pass DMD to her male offspring. Similarly, there's a 50% chance that her daughters will become carriers like her.

How does muscular dystrophy affect the Muscular System?

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Asked by Trichards

Muscular Dystrophy (abbr. MD) is a genetic disorder that DESTROYS MUSCLES that help the body move. As the muscle is destroyed they are replaced with fat and and connective tissue.

Source.: Textbook: Human Biology 11th edition, pg 268; Silvia S. Mader.

How many people die from muscular dystrophy each year?

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Asked by Wiki User

I am not sure exactaly but i hear 1 out of 2 boys are diagnost

What is muscle tissue?

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Asked by Wiki User

Muscle tissue accounts for nearly one-half of the total body weight and consists of three distinct subtypes:

• striated (skeletal) muscle

• smooth (visceral) muscle, and

• cardiac muscle

Each type of muscle cell is designed to perform one basic function.

Striated muscle is attached to bones that move the skeleton.

Smooth muscle is located in the walls of hollow internal structures, such as the intestines and blood vessels, allowing such organs to expand and contract.

Cardiac muscle occurs only in the heart, where it forms the walls and enables the heart to pump blood. When viewed under the light microscope, striated muscle cells appear long and thread-like with alternating light and dark cross strips called striations. In contrast, smooth muscle has no striations, Cardiac muscle cells, each of which has a nucleus, are slightly striated. Each cardiac muscle cell tends to divide into a "y" or "x" shape, so that it has more than two ends and joins more than two other cells, i.e., it intercalates. The ends of one cardiac muscle cell are separated from adjoining cells by a band called an intercalated disk.

Unlike skeletal muscle, smooth muscle and cardiac muscle are controlled involuntarily, i.e., an individual cannot stop or start the muscle action.

highly cellular and well vascularized

What experiments led Guillaume Duchenne to conclude that there were two types of smiles?

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Asked by Wiki User

he found out scientists were helping people with brain damage and saw the cingulate cortex and the motor cortez parts of the brain. . .

Typical microscopic changes in muscle tissue of someone with Duchenne's muscular dystrophy?

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Asked by Wiki User

Microscopic examination of the affected muscle would show the following changes:

A. degenerating skeletal muscle fibers (i.e. "cells").

B. proliferation of endomysium connective tissue around the degenerating muscle cells.

C. numerous macrophages (i.e. scavenger white blood cells) in the area, whose job it is to clear the cellular debris in the damaged muscle tissue.

D. while some of the muscle fibers are breaking down (as seen in a cross section), other fibers appear to be dense (or dark in color). These latter cells are presumably in a state of excessive contraction (i.e. more overlap between actin and myosin), probably because other segments of these cells (not in the microscopic viewing field) are experiencing breakdown of the cell membrane. Destruction of the cell membrane would of course, allow calcium ions to flow into the cell from the extracellular fluid (down their electrochemical gradient). As calcium floods the interior of these cells, it binds to troponin and causes a shift in tropomyosin, thus exposing the globular head binding sites on actin. Cross-bridges form and, in the muscle cell's "last breath," it contracts.

What is acceptable dlco level?

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Asked by Wiki User

It is variable, but on the machine I am tested on acceptable levels of DLCO range from 31.7 - 48.1. There are a number of other factors you need to pay attention to besides just this value. Talk with your doctor about these.

What is the life expectancy for person with myotonic muscular dystrophy?

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Asked by Wiki User

Persons with Becker MD may live until middle age.