Sickle-Cell Disease

Yes, sickle cell disease can affect the family in various ways. It may lead to emotional and financial stress, impact daily routines due to frequent medical appointments and hospitalizations, and require family members to provide support and care for the affected individual. Additionally, there can be genetic implications for family members regarding the risk of passing on the disease to future generations.

Yes, sickle-cell disease is caused by a genetic mutation in the hemoglobin gene, resulting in an error in the amino acid sequence of the hemoglobin protein. This mistake leads to the production of abnormal hemoglobin that causes red blood cells to become sickle-shaped, leading to various health problems.

The amino acid sequence of the sickle cell allele for hemoglobin varies from the normal allele for hemoglobin by one amino acid. The sickle cell allele for hemoglobin has valine instead of glutamic acid. When the oxygen level of the blood decreases, the hemoglobin molecules come out of solution, stick together, and form long chains that cause the red blood cells to become sickle shaped.

In sickle cell anemia, glutamic acid is replaced by valine due to a single base change in the gene that codes for hemoglobin. This substitution causes the hemoglobin protein to form abnormal sickle-shaped red blood cells, leading to the symptoms of the disease.

In sickle cell patients, a normal reticulocyte count is typically elevated due to the body's response to chronic hemolysis. The normal range for reticulocyte count in sickle cell patients is usually higher than in individuals without the disease, often ranging from 3% to 6%.

The mutation that causes sickle cell anemia leads to the production of abnormal hemoglobin, which causes red blood cells to become sickle-shaped. These sickle-shaped cells can block blood vessels, impairing blood flow and leading to episodes of pain, tissue damage, and increased risk of infections.

The body cannot fight against sickle cell anemia, its almost helpless. It relies on treatment, an outside source to help treat the disease. The immune system does try to destroy the affected red blood cells but its not very helpful.

It is a genetic mutation in countries that suffer from malaria. The malaria plasmodium parasite uses red blood cells during part of it's life cycle and the sickle shape of the normally round cell is a form of defence against the invading parasite.

Sickle-cell anemia is caused by a mutation in the gene that codes for hemoglobin, a protein that helps red blood cells carry oxygen. This mutation leads to the production of abnormal hemoglobin known as hemoglobin S, which causes red blood cells to become rigid and sickle-shaped. These sickle-shaped cells can block blood flow, leading to pain, organ damage, and other complications.

Although sickle cell anemia(SS) and sickle cell disease(SC) are considered genetic mutations, I believe the question is...What are possible causes for a sickle cell attack? Anything that causes a constriction of the blood vessels would seem to be a cause. Smoking, coffee, and alcohol to name a few. Dehydration also appears to play a big role.

rr since sickle cell is a recessive trait.

sickle cell anemia is a very painful disease people who have the disease have it from birth at which point during their youth they under go many treatments and people are constantly caring for them my advice is not to smoother someone who has the disease or treat it like a disability the best thing you can do is rub their back and give them space and some time you must remember that if this is a spouse, boyfriend or friend that they had the disease long before you came along and being overly helpful can come off as being over powering

I don't know what a communitive disease is, and neither does the dictionary, but sickle cell anemia is an inherited abnormality. I hope that helps.If you are asking if sickle cell is a disease in which you can catch from other people. The answer is No. It is an inherited Blood disorder.

Hemoglobin SS disease (Hb SS)

Sickle cell anemia is an inherited blood disorder that primarily affects individuals of African, Mediterranean, Middle Eastern, and South Asian descent. It is caused by a mutation in the hemoglobin gene, leading to the production of abnormal hemoglobin molecules that can result in red blood cells taking on a characteristic sickle shape.

polygenic inheritance .

doug says " squirrel". hes a fat dog.

Folic acid helps the body make red blood cells and can improve the symptoms of anemia by supporting the production of healthy red blood cells. However, folic acid supplements will not directly affect the underlying cause of sickle cell anemia, which is a genetic disorder affecting hemoglobin.

The organs afected by Sickle Cell Anemia is the heart and lungs...also the blood(blood cells) and bones

This disease is very serious. TEst for this disease before thinking about pregnancy because it goes automatically to your child adn ask your doctor ways to treat it- this disease can cause you pain your whole life. It runs in families.

When you walk past someone who sneezes. The anemia gets its sickle into your cells that way.

This is wrong^^^^

This is the correct answer: Sickle cell anemia is caused by an abnormal type of hemoglobin called hemoglobin S. Hemoglobin is a protein inside red blood cells that carries oxygen. Hemoglobin S changes the shape of red blood cells, especially when the cells are exposed to low oxygen levels. The red blood cells become shaped like crescents or sickles. ( its passed down from parents to offspring, if they have the trait )

The gene associated with sickle cell anemia is HBB, which is located in region 15.5 on the short arm of chromosome 11. There are many variations that can cause sickle cell, but primarily it is caused by the hemoglobin variant Hb S. According to the human genome project website: "the hydrophobic amino acid valine takes the place of hydrophilic glutamic acid at the sixth amino acid position of the HBB polypeptide chain. This substitution creates a hydrophobic spot on the outside of the protein structure that sticks to the hydrophobic region of an adjacent hemoglobin molecule's beta chain. This clumping together (polymerization) of Hb S molecules into rigid fibers causes the "sickling" of red blood cells." In a nutshell, when the hydrophobic (water fearing) amino replaces a hydrophilic one (water loving) on the protein chain, it creates a spot that sticks to another similar mutated gene, and they clump together, creating a sickle shaped cell. Looking at the location and incidence rates of sickle cell amenia, scientists believe that because malaria rates are high in the region, the body has created this defense against the disease -- an evolutionary self defense. Hope that helps :-)

No, sickle cell trait is a genetic condition that is inherited from one's parents and is not spread through kissing or any other form of casual contact. It is important to understand the genetic basis of sickle cell trait and discuss any concerns with a healthcare provider.

a child must inherit two copies of the defective gene in order to have a cystics fibrosis but when it come to sickle-cell anemia it is a disease passed down through families in which red blood cells from an abnormal sickle or crescent shape.Red blood cells carry oxygen to the body and are normally shaped like a disc so what causes sickle-cell anemia is the two copies that they get from both parents which gets passed down through families.

Sickle cell disease is caused by a mutation on chromosome 11, specifically in the HBB gene that codes for the beta-globin protein. This mutation leads to the production of abnormal hemoglobin, resulting in the characteristic sickle-shaped red blood cells.

Pleiotropy describes the genetic effect of a single gene on multiple phenotypic traits. The underlying mechanism is that the gene codes for a product that is for example used by various cells, or has a signalling function on various targets. A classic example of pleiotropy is the human disease PKU (phenylketonuria). This disease can cause mental retardation and reduced hair and skin pigmentation, and can be caused by any of a large number of mutations in a single gene that codes for an enzyme (phenylalanine hydroxylase) that converts the amino acid phenylalanine to tyrosine, another amino acid. Depending on the mutation involved, this results in reduced or zero conversion of phenylalanine to tyrosine, and phenylalanine concentrations increase to toxic levels, causing damage at several locations in the body. PKU is totally benign if a diet free from phenylalanine is maintained.