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Acetaminophen (Tylenol)
Tylenol is a drug brand in North America that reduces fever and pain and relieves the symptoms of flu, cough, cold and certain allergies. The active ingredient of this drug is acetaminophen, an antipyretic and analgesic drug.
1,628 Questions
Very few products contain gold in them today. One remaining example is a medication called Aurolate (gold sodium thiomalate) injection used for rheumatoid arthritis.
Why is acetaminophen not very effective in treating arthritis?
First off, acetaminophen is great for arthritis. This question stem is wrong, and I'll explain why.
Mediators of pain and inflammation are created in your body by an enzyme named cyclooxygenase (COX). This enzyme is therefore a target of drugs such as aspirin, ibuprofen, and perhaps acetaminophen amongst others. Aspirin and ibuprofen directly interact with this enzyme, binding it and thereby inhibiting it. Acetaminophen's mechanism is more or less unknown, but is thought to inhibit COX through another mechanism: scavenging COX's substrates. COX needs free radicals to function. These radicals are a reactant in the chemical reaction it catalyzes. Without radicals, COX cannot proceed.
When our immune system is fighting an a bug, our white blood cells release radicals to kill the infection. Sometimes our white blood cells perceive ourself as foreign, and mount a similar attack. Inflammation increases free radicals. If we take acetaminophen during an inflammatory process, the drug will be overwhelmed by all of the radicals (because it binds them, remember?) If the acetaminophen is exhausted, this means COX function will be uninterrupted. This makes acetaminophen less effective in managing the pain and inflammation secondary to an inflammatory process.
This being said, osteoarthritis (from degenerative changes/loss of cartilage) is NOT an inflammatory process (we don't know why steroid injections work), and so acetaminophen IS a great treatment for it. This is especially true because osteoarthritis is a long term problem that requires long term treatment, and ibuprofen or aspirin or naproxen etc. would likely cause peptic ulcers if taken that long, and so acetaminophen is a first line choice. This question stem is misleading and incorrect. Celecoxib/celebrex is an NSAID selective for cox 2 enzyme, easier on the stomach and another option for long term pain control of osteoarthritis.
Acetaminophen would NOT be a great choice for arthritis from an inflammatory etiology, such as rheumatoid, or connective tissue diseases like lupus, for the reasons before explained. Acetaminophen is also not the best choice for any pain caused by tissue injury (back sprain, torn ligament etc) because of reasons explained before (excess free radical release from WBC's cleaning up the mess).
There is more to acetaminophen's mechanism than we understand. It apparently doesn't inhibit COX all that much, because COX enzyme is critical in making prostaglandins that dilate the kidney's arterioles. NSAIDS are a big no no in someone who is old with already low kidney function or in someone with bad kidney disease like diabetes. However, acetaminophen is great for pain management in people with kidney malefaction because, although we believe it inhibits COX via scavenging radicals, it apparently doesn't have a big enough effect on COX to inhibit prostaglandins and cause a decrease in GFR.
How long can an embalmed body remain preserved?
There are many variables involved. What materials were used in the embalming process? Was the body buried in a desert? Type of casket and vault? With good embalming methods and the right conditions it could be years.
It all depends on religion. Muslims would prey and then bury right away, For the orthodox people burring he body can take some time, with all the prayers, and rituals In accordance with the Jewish tradition, Jews want to bury the dead within 24 hours, except when the death occurs on Friday after sundown, on Saturday, on a Jewish holiday, or when waiting for family members to arrive.
Is 500 mg Acetaminophen an OSHA Recordable?
No. It is only OSHA recordable if the Over the Counter (OTC) recommended doseage is exceeded. If the OTC doseage is not exceeded, it is considered first aid.
However if the daily maximum doseage is no more than 2 pills (1000mg) 3 times per day (total of 3000mg), and the physician prescribes the patient to take more than 2 pills at a time or more than 6 pills in a 24 hour period then the recommended OTC doseage is exceeded and it would be considered recordable by OSHA.
Why do cats die when they eat paracetamol?
Cats lack a specific liver enzyme necessary to breakdown paracetamol effectively, leading to the accumulation of toxic byproducts that can cause severe damage to their red blood cells and liver, potentially resulting in organ failure and death. It is important to never give paracetamol to cats and to seek immediate veterinary care if ingestion is suspected.
1.21 tsp
1 milliliter equals 0.202 US teaspoons.
1 teaspoon is 4.92 milliliters
Should children over fifteen take their own decision about their life?
Yes, they should be allowed to make their own decision, if you believe in them.
How Can We Help Children in Decision-Making?
Stonebridge Academy McKinney Blog
1 teaspoon1/3 tablespoon5 ml 1 teaspoon1/3 tablespoon5 ml
5 ml = 1 Teaspoon or 1/3 tablespoon so 8 ml is very close to 1 1/2 + a little bit
close enough for cooking, but for drugs do the math.
I think you're mistaken. Naproxen is Aleve, Ibuprofen is an NSAID (non steroidal anti inflammatory drug), and Tylenol is acetaminophen.
Vicodin is a combination of acetaminophen and hydrocodone. The hydrocodone is a narcotic (opiate).
Combining two OTC pain medications is generally a bad idea as you'll combine the bad effects (i.e. stomach bleeding, taxing your liver) and you really won't get much more bang for your buck.
So to answer your question, none of the above.
Can Tylenol and Excedrin Migraine be taken together?
No. You should check the ingredients in the Excedrin Migraine. Two tablets contain 500 mg of aspirin and 500 mg of acetaminophen plus 65 mg of caffeine. You should not take more aspirin. It can cause stomach bleeding. If that dose is ineffective perhaps you should be evaluated by a neurologist and try to find a prescription drug to treat your migraines. There are several extremely ones available.
What pain reliever can a pregnant woman take safely?
Tylenol or acetaminophen is the safest pain releiver for pregnant women and children. Although NSAIDS like ibuprofen are relatively safe Tylenol is considered the safest. The worst pain reliever to be used is aspirin because it is a blood thinner and if a child is taking it while exposed to a virus like the chicken pox then they can get Reyes syndrome and that isn't good.
Where did hydrocodone bitartrate and acetaminophen originate?
First created in the 1920's by German pharmaceutical company Knoll, Hydrocodone is created by attaching a hydrogen atom to codeine molecules. When it was first released, Knoll believed that this process would make the codeine easier on the stomach and less toxic to the user.
During this time, medical and government officials in the United States were coping with a growing problem: thousands of people across the country were becoming addicted to the opiate ingredients found in the most popular cough syrups of the day. At the end of the 1920's the U.S. Bureau of Social Hygiene funded a study by the National Research Council to examine hydrocodone and other drug compounds as alternative, less-addictive painkillers.
The National Research Council named renowned University of Michigan pharmacologist Dr. Nathan Eddy to head up the study. He studied the effects, safety and side effects of hundreds of different drugs, including heavy-hitters such as morphine, codeine and the up-and-coming hydrocodone.
After a series of ethically-questionable tests on cats to determine the "analgesic" effect of the drugs, Eddy found hydrocodone was one of the most effective drugs in the study in terms of pain killing effectiveness and the predictably of its side effects. There was however, a problem with hyrocodone - is created a tremendous euphoric effect in the animals studied. He felt that the drug was powerful, but that it also held the potential to be highly addictive. In fact, he went on to say that it would be possible for an individual to become addicted to hydrocodone without even realizing it.
Despite Eddy's findings, hydrocodone became a hit on the U.S. market and in the years that followed, grew in popularity as a pain reliever despite its addictive potential.
The current state of HydrocodoneCurrently doctors face stiff penalties if mis-prescribing hydrocodone to a patient. These same physicians are also coping with an addicted patient base - many of whom will lie about illnesses or "doctor shop" in order to gain access to additional prescriptions for the drug. As we move through the 21st century, hydrocodone addiction remains a growing problem in our community.What is the cause of burning in your throat after swollowing a pill with hot coffee?
my theory is that the hot liquid starts to break down the medicatin in your mouth rather in your stomach, the medication begins to absorb in your throat and that is what causes a burning sensation
