Lupus

An ANA (antinuclear antibody) test is a blood test used to detect the presence of antibodies that may indicate autoimmune disorders. A reflex titer is a follow-up test that is automatically performed if the initial ANA test result is positive, measuring the concentration of these antibodies. This helps in assessing the likelihood of autoimmune diseases, such as lupus or rheumatoid arthritis, and guiding further diagnosis and treatment. A higher titer indicates a greater level of antibodies, which can correlate with disease activity.

Lupus signs can vary widely but commonly include fatigue, joint pain or swelling, a butterfly-shaped rash across the cheeks and nose, and sensitivity to sunlight. Other symptoms may include fever, hair loss, mouth sores, and kidney problems. Because lupus can affect multiple organs, symptoms can differ significantly among individuals. Early diagnosis and management are crucial for effective treatment.

Yes, a lupus patient can undergo lap-band surgery, but it requires careful evaluation by their healthcare team. Factors such as the severity of the lupus, the patient's overall health, and the presence of any complications must be considered. It's essential for the patient to consult with both their rheumatologist and a bariatric surgeon to ensure that the surgery is safe and appropriate for their specific condition. Close monitoring post-surgery is also crucial due to potential complications related to lupus.

In Greek, lupus is referred to as "λύκος" (pronounced "lykos"). The term literally translates to "wolf," as the name lupus is derived from the Latin word for wolf. In medical contexts, lupus is often referred to as "ερυθηματώδης λύκος" (erythematous lupus) to specify the autoimmune condition.

Lupus is a chronic, inflammatory, autoimmune disease that can affect any part of the body including the thyroid. People who have one autoimmune disease usually have other autoimmune diseases in overlap. It is possible for lupus to affect the thyroid, but autoimmune thyroid disease like Hashimoto's thyroiditis could be responsible.

Lupus, specifically systemic lupus erythematosus (SLE), was first described in the 19th century, with significant contributions from several physicians. The term "lupus" itself, meaning "wolf" in Latin, was used by physician Thomas Addison in the 1850s to describe skin lesions resembling wolf bites. While no single individual "discovered" lupus, the understanding of the disease has evolved through the work of many researchers over time. Notably, the development of serological tests in the mid-20th century greatly advanced the diagnosis and understanding of lupus.

The exact cause of lupus is not known. Lupus is an autoimmune disease where the body's immune system is confused and attacks healthy parts of the self. Researchers believe that if a person inherits just the right combination of genes (genetic predisposition) and is exposed to certain triggers, either extreme or over a period of time, lupus will develop. Lupus is not directly hereditary like sickle cell disease. Lupus is not contagious. You can't catch in from someone or give it to someone. The Epstein-Barr virus (the one that causes mononucleosis) is often cited as a trigger. Other triggers include stress, sunlight, cigarette smoke, and certain medications. The medications are the one given for tuberculosis and some high blood pressure medications. If the lupus is drug induced, the lupus goes away once the offending drug is withdrawn.

The average age of death in individuals with systemic lupus erythematosus (SLE) can vary significantly, but studies suggest that it is often around 10 to 20 years earlier than the general population. The median age of death for SLE patients is typically in the late 40s to early 50s. Factors such as disease severity, organ involvement, and access to healthcare can influence survival rates and life expectancy in those with the condition. Improved management and treatment have contributed to better outcomes over recent years.

Lupus, specifically systemic lupus erythematosus (SLE), can affect the liver through autoimmune mechanisms, leading to inflammation and damage. The condition can cause liver dysfunction, manifesting as elevated liver enzymes, and may lead to conditions like autoimmune hepatitis or drug-induced liver injury from medications used to treat lupus. Additionally, lupus can increase the risk of developing fatty liver disease. Regular monitoring of liver function is important for managing lupus patients.

Lupus itself is not directly related to low sodium levels, but certain medications used to manage lupus or complications from the disease can lead to hyponatremia (low sodium). Additionally, some individuals with lupus may experience kidney issues that affect sodium balance. It's important for patients with lupus to monitor their sodium levels and discuss any concerns with their healthcare provider.

Women with lupus should consult their healthcare provider before taking soy isoflavones. While some studies suggest potential benefits, soy can interact with medications and may not be suitable for everyone, especially those with autoimmune conditions. It’s essential to consider individual health circumstances and potential risks. Always prioritize guidance from a medical professional.

Lupus itself does not have a specific odor. However, some individuals with lupus may experience skin rashes or infections that could produce an odor. Additionally, certain medications or conditions related to lupus might lead to changes in body odor. It's important to consult a healthcare professional for any concerns regarding symptoms.

Self-inducing a lupus flare is not advisable, as it can lead to serious health complications. However, certain factors may trigger flares in susceptible individuals, such as excessive sun exposure, stress, infections, and certain medications. It's crucial to manage lifestyle factors and work with a healthcare provider to minimize risks and maintain overall health. If you suspect a flare, consult your doctor for appropriate guidance and management strategies.

There is not just one test for Lupus. The Dx involves lab work, pt. history, and exam. Some of the tests are expensive and must unfortunately be repeated. Your best resource for tests and explanations of Lupus is the Lupus Foundation website. www.lupus.org

I'm no doctor, but I am an HS patient and yes, I think they are related. I don't understand why HS hasn't been classified as an auto-immune disease officially.

Lupus is a remitting flaring autoimmune disease that affects each patient differently. When lupus is flaring, inflammation markers like sed rate, ferratin, and c reactive protein are likewise high.

An positive ANA (antinuclear antibody) means that you make antibodies that attack the circulating debris of the nucleii of your own cells that have died. A titer of 320 means that your blood had to be diluted320 times before they got a sample that had no antinuclear antibody. Typically the numbers are 40, 80, 160, 320, 640, and so on. Lupus presents a speckled pattern, not a nucleolar pattern.

10 million Americans have a positive ANA. Only 1.5 million have lupus. Many people have a positive ANA and no active disease of any kind. Unless you are having some kind of symptoms, don't be overly concerned.