Sicily is an autonomous region of Italy and it's largest island. Taken from Answers.com: .
The island was once a city-state in its own right, and as the Kingdom of Sic…ily ruled from Palermo over southern Italy, Sicily, and Malta. It later became a part of the Two Sicilies under the Bourbons, a kingdom governed from Naples that comprised both the island itself and most of southern Italy. The Italian unification of 1860 led to the dissolution of this kingdom, and Sicily became an autonomous part of the Kingdom of Italy. Sicily is today an autonomous region of Italy. Of all the regions of Italy, Sicily covers the largest land area at 25,708 square kilometres (9,926 sq mi) and currently has just over five million inhabitants. ( Full Answer )