Maps and Directions

I think you mean Fargo, North Dakota; there is no Fargo is South Dakota.

As for the route:

1. Take I-70 WEST to I-70/76 Pennsylvania Turnpike (toll road) WEST to PITTSBURGH in Breezewood, PA. Follow signs.
2. Take the Pennsylvania Turnpike WEST on I-70/76 and I-76 to Ohio where it becomes the Ohio Turnpike (toll road). Take the Ohio Turnpike (toll road) WEST on I-76, I-80 and I-80/90 to Indiana where it becomes the Indiana TOLL ROAD.
3. Take the Indiana TOLL ROAD WEST on I-80/90 to I-80 WEST at EXIT 21 in northeastern Indiana (Chicagoland).
4. Continue on I-80 WEST through Indiana and Illinois to I-680 WEST to NORTH OMAHA and SIOUX CITY at EXIT 27 in Iowa.
5. Take I-680 WEST to I-29 NORTH to SIOUX CITY at EXIT 13B.
6. Take I-29 NORTH through Iowa and South Dakota to Fargo, NORTH DAKOTA.

464 miles

However, driving-wise it is 550 miles taking this route:

1. Take I-70 EAST (towards ST. LOUIS), from Independence, to I-64 EAST to LOUISVILLE, via I-270 NORTH (EXIT 232A off I-70 to get onto I-270 NORTH) & I-255 SOUTH to bypass ST. LOUIS, MO (EXIT 7 off I-270 in ILLINOIS to get onto I-255 SOUTH ; EXIT 20 off I-255 to get onto I-64 EAST to LOUISVILLE).
2. Take I-64 EAST to I-57 SOUTH to MEMPHIS.
3. Continue on I-57 SOUTH to I-24 EAST to NASHVILLE at EXIT 44.
4. Take I-24 EAST to Nasvhille.

It is approximately 74 freeway miles on I-45 SOUTH from Spring, Texas, north of Houston, to Galveston, Texas, on the gulf of Mexico.

See related links below for a map.

Additional information:

Depending on the time of day and day of week, this trip could take well over two hours, since the route is fully across the Houston area from north to south, and through the downtown business area. Plan the travel time accordingly to avoid the "rush hours".